Bone Tumors

Bone Tumors: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore: Inspection (viewing). Skin and mucous membranes [broad ulcerated (“ulcerated”) nodule in cutis (skin) and subcutis (subcutaneous) (palpable) (usually painless/poor)?] Mouth, teeth [due todifferential diagnosis: reparative giant cell granuloma … Bone Tumors: Examination

Bone Tumors: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests. Biopsy (tissue sample) – to determine the type of tumor as well as its aggressiveness; most important diagnostic measure in cases of suspected tumor; performed following imaging procedures (see “Medical Device Diagnostics“). Alkaline phosphatase (AP) isoenzymes, ostase, urinary calcium (the tumor hypercalcemia (synonym: tumor-induced hypercalcemia, TIH) is … Bone Tumors: Test and Diagnosis

Bone Tumors: Drug Therapy

Therapeutic targets Relief of pain Stabilization of bone sections at risk of fracture Prevention or improvement of existing neurological deficits in bone tumors in the skull or vertebrae. Reduction of tumor size – preoperatively (before surgery) by radiotherapy (radiotherapy) or chemotherapy (neoadjuvant chemotherapy). Removal of the tumor – see “Surgical therapy“. Healing Therapy recommendations Therapy … Bone Tumors: Drug Therapy

Bone Tumors: Diagnostic Tests

Mandatory medical device diagnostics. Sonography (ultrasound examination) Conventional X-ray of the affected body region, in two planes – to assess the extent of tumor growth and possibly also the type, as well as its dignity (biological behavior of tumors; i.e., whether they are benign (benign) or malignant (malignant)); blurred defects in the bone substance indicate … Bone Tumors: Diagnostic Tests

Bone Tumors: Surgical Therapy

For benign (benign) tumors, the goal is complete excision (curettage).For malignant (malignant) tumors, the goal is removal in healthy tissue with a safety margin. The following forms of surgical therapy are available and are performed depending on the exact tumor type: Biopsy (tissue removal) to clarify the dignity (biological behavior of tumors; i.e., whether they … Bone Tumors: Surgical Therapy

Bone Tumors: Medical History

Medical history (history of illness) represents an important component in the diagnosis of bone tumors. Family history Are there any diseases in your family that are common? (Tumor diseases) Social anamnesis Current medical history/systemic history (somatic and psychological complaints). Do you suffer from persistent or increasing pain in the skeletal system for which there is … Bone Tumors: Medical History

Bone Tumors: Or something else? Differential Diagnosis

Respiratory System (J00-J99) Maxillary sinus empyema – accumulation of pus in the maxillary sinuses. Maxillary sinus mycosis Jaw cysts Ostitis fibrosa – painless distension of the forehead and maxilla (upper jaw bone). Pneumosinus dilatans (rare) – dilatation (dilation) of the paranasal sinuses due to impaired valve mechanism. Sinusitis (inflammation of the paranasal sinuses). Endocrine, nutritional … Bone Tumors: Or something else? Differential Diagnosis

Bone Tumors: Consequential Diseases

The following are the most important diseases or complications that may be contributed to by bone tumors: Respiratory system (J00-J99) Obstruction of the excretory duct of the paranasal sinus → paranasal sinus mucocele (mucocele = accumulation of mucus) (osteoma). Endocrine, nutritional and metabolic diseases (E00-E90). Amyloidosis – extracellular (“outside the cell”) deposits of amyloids (degradation-resistant … Bone Tumors: Consequential Diseases

Bone Tumors: Classification

The most common classification of bone tumors is by dignity, that is, whether they are benign (benign) or malignant (malignant): Benign tumors Tissue of origin Benign fibrous histiocytoma Connective tissue Chondroblastoma (Codman tumor) Cartilage tissue Desmoplastic bone fibroma Connective tissue Enchondroma Cartilage tissue Fibrous bone dysplasia (Jaffe-Lichtenstein) Connective tissue Bone hemangioma Vessels Nonossifying fibroma (NOF) … Bone Tumors: Classification

Bone Tumors: Radiotherapy

Radiatio can be used as the sole treatment for bone tumors or in combination with tumor resection (surgical removal of the tumor). Radiatio is used for the following bone tumors: Ewing’s sarcoma (primary malignant/malignant). Plasmocytoma (primary malignant) Osteosarcoma – palliative (without curative approach) (primary malignant). Bone metastases – palliative → analgesic and recalcifying (secondary malignant).

Bone Tumors: Symptoms, Complaints, Signs

The clinical presentation of bone tumors depends on the tumor type, size or extent, location, and stage. Benign (benign) bone tumors are usually asymptomatic and therefore usually an incidental finding on radiography. The following symptoms and complaints may indicate malignant (malignant) bone tumors: Main symptoms Pain that also occurs at rest and/or at night and … Bone Tumors: Symptoms, Complaints, Signs

Bone Tumors: Causes

Pathogenesis (development of disease) Different bone tumors develop in different ways. Depending on the tissue from which the neoplasm originates, the following classification of bone tumors results: Osseous tumors – originate from osteoclasts (cells that break down bone) or osteoblasts (cells that break down bone). Osteoblastoma (synonym: giant osteoid osteoma) (benign/benign). Osteoid osteoma (benign) Osteoma … Bone Tumors: Causes