The following are the most important diseases or complications that may be contributed to by bone tumors: Respiratory system (J00-J99) Obstruction of the excretory duct of the paranasal sinus → paranasal sinus mucocele (mucocele = accumulation of mucus) (osteoma). Endocrine, nutritional and metabolic diseases (E00-E90). Amyloidosis – extracellular (“outside the cell”) deposits of amyloids (degradation-resistant … Bone Tumors: Consequential Diseases
The most common classification of bone tumors is by dignity, that is, whether they are benign (benign) or malignant (malignant): Benign tumors Tissue of origin Benign fibrous histiocytoma Connective tissue Chondroblastoma (Codman tumor) Cartilage tissue Desmoplastic bone fibroma Connective tissue Enchondroma Cartilage tissue Fibrous bone dysplasia (Jaffe-Lichtenstein) Connective tissue Bone hemangioma Vessels Nonossifying fibroma (NOF) … Bone Tumors: Classification
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore: Inspection (viewing). Skin and mucous membranes [broad ulcerated (“ulcerated”) nodule in cutis (skin) and subcutis (subcutaneous) (palpable) (usually painless/poor)?] Mouth, teeth [due todifferential diagnosis: reparative giant cell granuloma … Bone Tumors: Examination
In esophageal cancer – colloquially called esophageal cancer – (synonyms: Abdominal esophageal carcinoma; Barrett’s carcinoma; Barrett’s esophagus; malignant neoplasm of the pars abdominalis of the esophagus; malignant neoplasm of the pars cervicalis of the esophagus; malignant neoplasm of the pars thoracica of the esophagus; malignant neoplasm of esophagus; malignant neoplasm of abdominal esophagus; malignant neoplasm … Esophageal Cancer: Symptoms, Causes, Treatment
Pathogenesis (disease development) Neuroblastoma develops from immature neural cells in neurons of the sympathetic nervous system and in the adrenal gland. In a proportion of cases, the n-myc oncogene is amplified (multiplied). Etiology (Causes) The etiology is still unknown. Biographic causes Genetic burden from parents, grandparents (very rare). Genetic risk depending on gene polymorphisms: Genes/SNPs … Neuroblastoma: Causes
General measures Nicotine restriction (refraining from tobacco use). Limited alcohol consumption (men: max. 25 g alcohol per day; women: max. 12 g alcohol per day). Preservation of normal weight strive!Determination of BMI (body mass index, body mass index) or body composition using electrical impedance analysis. Falling below the BMI lower limit (from the age of … Neuroblastoma: Therapy
Nonossifying fibroma (NOF) (synonyms: nonossifying bone fibroma; nonosteogenic fibroma; fibrous cortical defect; fibrous cortical defect; fibroxanthoma; cortical fibroma; medullary fibroma; metaphyseal defect; benign cortical defect; benign histiocytic fibroma; histiocystic xanthogranulum; ICD-10 D16. -: Benign neoplasm of bone and articular cartilage) refers to a benign (benign) tumor-like lesion of bone (“tumor-like lesions”; tumor-like mass) caused by … Nonossifying Fibroma
Medical history (history) is an important component in the diagnosis of nonossifying fibroma (NOF). Family history Are there any diseases in your family that are common? (Tumor diseases) Social anamnesis Current medical history/systemic history (somatic and psychological complaints). Do you suffer from persistent or increasing pain in the skeletal system for which there is no … Nonossifying Fibroma: Medical History
Musculoskeletal system and connective tissue (M00-M99). Aneurysmal bone cyst – aggressive, expansive growing cyst. Fibrous dysplasia – malformation of bone tissue, that is, the bones form tumor-like protrusions. Neoplasms – tumor diseases (C00-D48). Benign (benign) fibrous histiocytoma (BFH; synonym: dermatofibroma). Chondroma, periosteal (affecting the periosteum) – benign tumor that forms mature cartilage tissue. Symptoms and … Nonossifying Fibroma: Or something else? Differential Diagnosis
The following are the most important diseases or complications that may be contributed to by nonossifying fibroma (NOF): Injury, poisoning, and other sequelae of external causes (S00-T98). Pathologic fractures (broken bones) – due to the bone tumor, the affected bone loses strength
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse,body weight, height; furthermore: Inspection (viewing). Skin and mucous membranes Extremities Gait pattern (fluid, limping) Auscultation (listening) of the heart. Auscultation of the lungs Palpation (palpation) of the painful area [pressure pain, pain on movement, pain … Nonossifying Fibroma: Examination
Therapeutic targets Relief of pain – non-osseous fibroma usually causes pain very rarely. Stabilization of bone sections at risk of fracture Healing Therapy recommendations Analgesia according to WHO staging scheme: Non-opioid analgesic (paracetamol, first-line agent). Low-potency opioid analgesic (e.g., tramadol) + non-opioid analgesic. High-potency opioid analgesic (eg, morphine) + non-opioid analgesic.
