Squamous Cell Carcinoma of the Skin: Causes

Pathogenesis (disease development) UV radiation, X-rays, and chemical carcinogens cause DNA damage to the skin (signature mutations). These are only partially repaired, so that mutations (changes in genetic material) lead to malignant proliferation (“malignant proliferation”) of keratinocytes (“horn-forming cells”) of the skin or skin appendages. Squamous cell carcinoma (PEC) of the skin usually develops on … Squamous Cell Carcinoma of the Skin: Causes

Squamous Cell Carcinoma of the Skin: Therapy

General measures Nicotine restriction (refraining from tobacco use). Limited alcohol consumption (men: max. 25 g alcohol per day; women: max. 12 g alcohol per day). Review of permanent medication due topossible effect on the existing disease. Avoidance of environmental stress: Chronic exposure to heat Occupational contact with carcinogens such as polycyclic aromatic hydrocarbons (PAHs), arsenic, … Squamous Cell Carcinoma of the Skin: Therapy