Lymphogranuloma Venereum

Lymphogranuloma Venereum: Medical History

Medical history (history of illness) represents an important component in the diagnosis of lymphogranuloma venereum. Family history Social history What is your occupation? Do you travel abroad frequently? Asia, Africa, South America? Current medical history/systemic history (somatic and psychological complaints). Have you noticed painless vesicles that ulcerate? Have you noticed purulent lymph node enlargement? Do … Lymphogranuloma Venereum: Medical History

Lymphogranuloma Venereum: Or something else? Differential Diagnosis

Skin and subcutaneous (L00-L99). Hidradenitis suppurativa – misleading term because the disease does not originate from sweat glands but from sebaceous glands and terminal hair follicles; chronic, inflammatory disease at terminal follicles of skin envelope folds that can lead to marked scarring and disability [to be excluded at stage III]. Infectious and parasitic diseases (A00-B99). … Lymphogranuloma Venereum: Or something else? Differential Diagnosis

Lymphogranuloma Venereum: Complications

The following are the most important diseases or complications that may be contributed to by lymphogranuloma venereum: Respiratory system (J00-J99) Pleurisy (pleurisy). Pneumonitis (collective term for any form of pneumonia (lung inflammation), which does not affect the alveoli (alveoli), but the interstitium or intercellular space). Eyes and eye appendages (H00-H59). Conjunctivitis (conjunctivitis). Skin – subcutaneous … Lymphogranuloma Venereum: Complications

Lymphogranuloma Venereum: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore: Inspection (viewing). Skin Mucous membranes [symptom: painless vesicle, which then ulcerates (called primary lesion)] Inguinal region (groin region) [symptom: painful purulent lymph node disease (lymphadenopathy); occurs after several … Lymphogranuloma Venereum: Examination

Lymphogranuloma Venereum: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests. Microscopic of the bacterial species Chlamydia trachomatis by immunofluorescence. Detection of serotypes L1-L3 of the bacterial species Chlamydia trachomatis [acute LGV infection fourfold increase in antibody titers; CFT > 1:64, MIFT > 1:128]. DNA detection of Chlamydia trachomatis by “nucleic acid amplification tests” (NAAT) (gold standard; sensitivity … Lymphogranuloma Venereum: Test and Diagnosis

Lymphogranuloma Venereum: Drug Therapy

Therapeutic targets Elimination of the pathogens (serotypes L1-L3 of the bacterial species Chlamydia trachomatis). Avoidance of complications Therapy recommendations Antibiosis (antibiotic therapy; first-line agents in the primary and secondary stages of the disease: doxycycline; azithromycin; in pregnancy: erythromycin). Duration of therapy Primary and in the secondary stage: at least 3 weeks. Tertiary stage: case-adapted antibiotic … Lymphogranuloma Venereum: Drug Therapy

Lymphogranuloma Venereum: Prevention

To prevent lymphogranuloma venereum, attention must be paid to reducing risk factors. Behavioral risk factors Sexual transmission Promiscuity (sexual contact with relatively frequently changing different partners). Prostitution Men who have sex with men (MSM). Sexual contacts in the vacation country Unprotected coitus Sexual practices with high risk of mucosal injury (e.g., unprotected anal intercourse).

Lymphogranuloma Venereum: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate lymphogranuloma venereum: Leading symptoms Painless papule (vesicle) or pustule (pustule), which then disintegrates ulcerously (“ulcerated”) (so-called primary lesion) [changes at the site of infection]. Painful unilateral or bilateral regional lymphadenopathy (enlargement of the lymph nodes; if the lymph nodes melt in with pus, they are called bubones (Latin … Lymphogranuloma Venereum: Symptoms, Complaints, Signs

Lymphogranuloma Venereum: Causes

Pathogenesis (development of disease) Infections with Chlamydia trachomatis (intracellular bacterium that feeds on the ATP of the cell as an energy parasite) are usually transmitted via unprotected coitus. The bacteria attach themselves to the cells of the urogenital tract (urinary and genital tract) and/or respiratory tract (respiratory tract) and subsequently invade them. There they multiply … Lymphogranuloma Venereum: Causes