Medical history (history of illness) represents an important component in the diagnosis of Sindbis fever. Family history What is the general health of your family members? Social history What is your profession? Have you been abroad recently? In rural areas? Current medical history/systemic history (somatic and psychological complaints). What symptoms have you noticed? How long … Sindbis Fever: Medical History
Infectious and parasitic diseases (A00-B99). Viral infections, unspecified Musculoskeletal system and connective tissue (M00-M99). Reactive arthritis (synonym: postinfectious arthritis) – secondary disease after gastrointestinal, urogenital, or pulmonary infections; refers to arthritis in which pathogens are (usually) not found in the joint (sterile synovitis). Reactive arthritis (synonym: postinfectious arthritis / joint inflammation) – second disease after … Sindbis Fever: Or something else? Differential Diagnosis
The following are the most important diseases or complications that may be contributed to by Sindbis fever: Musculoskeletal system and connective tissue (M00-M99). Long-lasting/persistent arthralgia (joint pain). Long lasting/persistent arthritis (inflammation of the joints)
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes, and sclerae (white part of the eye) [exanthema (rash), maculopapular (blotchy and with papules, i.e., vesicles) or morbiliform (measles-like); begins on the trunk of the body … Sindbis Fever: Examination
Laboratory parameters of the 1st order – obligatory laboratory tests. Pathogen detection from blood (PCR/polymerase chain reaction, virus culturing). Detection of IgM, IgG on the 8th day possible. Small blood count Differential blood count Inflammatory parameter – CRP (C-reactive protein)
Therapeutic target Pain relief Therapy recommendations Symptomatic therapy (analgesics/pain relievers, antipyretics/antipyretic drugs, if necessary).
Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics, and obligatory medical device diagnostics – for differential diagnostic clarification. Radiographs of the affected joints
To prevent Sindbis fever, attention must be paid to reducing risk factors. Behavioral risk factors Bite of a mosquito Frequent stay in forests of endemic areas. General prophylactic measures Wearing clothing that covers the body Use of repellents Removal of mosquito breeding sites
The following symptoms and complaints may indicate Sindbis fever: General feeling of illness Fever Cephalgia (headache) Arthralgia (joint pain) Arthritis (inflammation of the joints) with severe restrictions of movement; may affect several joints and migrate Exanthema (rash), maculopapular ((patchy and with papules, ie with vesicles)) or morbiliform (measles-like); starts on the trunk of the body … Sindbis Fever: Symptoms, Complaints, Signs
Pathogenesis (development of disease) Sindbis virus, with its Ockelbo and Babanki virus subtypes, belongs to the Togaviridae family. It is transmitted by mosquitoes of the genus Culex, but also Aedes. Etiology (Causes) Behavioral causes Bite of a mosquito Frequent stay in forests of endemic areas.
General measures in case of infection Symptomatic therapy
