Products Fenticonazole is no longer on the market in many countries (Mycodermil Crème, Gyno-Mycodermil, Crème). Structure and properties Fenticonazole (C24H20Cl2N2OS, Mr = 455.4 g/mol) is present in drugs as fenticonazole nitrate, a white crystalline powder that is practically insoluble in water. It is a racemate. Effects Fenticonazole (ATC D01AC12, ATC G01AF12) has antifungal properties; see … Fenticonazole
Products Tolnaftate is commercially available as an ointment (Undex, combination). Quadriderm ointment is out of commerce. Structure and properties Tolnaftate (C19H17NOS, Mr = 307.4 g/mol) exists as a white to yellowish white powder that is practically insoluble in water. Effects Tolnaftate (ATC D01AE18) has fungistatic to fungicidal properties. Indications Fungal infections with susceptible pathogens.
Products Butenafine is not commercially available in many countries. In other countries, it is available as a cream (e.g., Mentax) and other products. Structure and properties Butenafine (C23H27N, Mr = 317.5 g/mol) is present in drugs as butenafine hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a naphthalene derivative and … Butenafine
Products Butoconazole vaginal cream is no longer available in many countries (Gynazole). It is on the market in other countries. Structure and properties Butoconazole (C19H17Cl3N2S, Mr = 411.8 g/mol) is present in drugs as butoconazole nitrate, a white crystalline powder that is practically insoluble in water. It is a chlorinated imidazole derivative. Effects Butoconazole (ATC … Butoconazole
Products Fluconazole is commercially available in capsule form, as a powder for suspension, and as an infusion solution (Diflucan, generic). It has been approved in many countries since 1989. Structure and properties Fluconazole (C13H12F2N6O, Mr = 306.3 g/mol) is a fluorinated triazole derivative. It exists as a white, crystalline and hygroscopic powder that is sparingly … Fluconazole
Products Flucytosine is commercially available as an infusion solution (Ancotil). Although it would also be available orally, in many countries only drugs for parenteral administration are available. Structure and properties Flucytosine (C4H4FN3O, Mr = 129.1 g/mol) is a nucleoside analog of the pyrimidine base cytosine. Effects Flucytosine (ATC D01AE21, ATC J02AX01) has antifungal (fungistatic) properties. … Flucytosine
Products Terbinafine is commercially available in tablet form (Lamisil, generic). It has been approved in many countries since 1991. Structure and properties Terbinafine (C21H25N, Mr = 291.4 g/mol) is present in drugs as terbinafine hydrochloride, a white powder that is very sparingly soluble in water. It is an allylamine and naphthalene derivative. Effects Terbinafine (ATC … Terbinafine (Nail Fungus)
Products Terbinafine cream has been approved in many countries since 1991 (Lamisil, generic). Structure and properties Terbinafine (C21H25N, Mr = 291.43 g/mol) is present in the drug as terbinafine hydrochloride, a white crystalline powder that is sparingly soluble in water. It belongs structurally to the allylamines. Effects Terbinafine (ATC D01AE15) has fungistatic to fungicidal properties … Terbinafine Cream
