Products In 2009, a water-soluble varnish containing 8% ciclopirox was approved in many countries for the treatment of nail fungus, which is applied once daily (Ciclopoli). It went on sale in January 2011. In many countries, ciclopirox 8% had already been approved for the treatment of nail fungus for a number of years, in France … Ciclopirox against Nail Fungus
Products Tioconazole is no longer available in many countries. Trosyd is out of commerce. Structure and properties Tioconazole (C16H13Cl3N2OS, Mr = 387.7 g/mol) Effects Tioconazole (ATC D01AC07, ATC G01AF08) is antifungal. Indications Fungal infections
Products Azole antifungals are approved in many countries for both topical and systemic treatment. They are available in numerous dosage forms-including creams, an oral gel, powders, sprays, tablets, capsules, injectables, vaginal creams, and vaginal tablets. The first azole antifungal came on the market in the 1950s. Structure and properties The name azole refers to heterocycles … Azole Antifungals
Products Undecylenic acid is commercially available in many countries as an ointment (Undex, combination preparation). Solutions and creams are also available in some countries. Undecylenic acid has been used medicinally for many decades. Undex ointment has been approved in many countries since 1951. Structure and properties Undecylenic acid (C11H20O2, Mr = 184.3 g/mol) exists as … Undecylenic Acid
Products Tavaborole was approved in the United States in 2014 as a solution for external use (Kerydin). The drug is not currently registered in many countries. Structure and properties Tavaborole (C7H6BFO2, Mr = 151.9 g/mol) exists as a white powder that is sparingly soluble in water. It is an organic boron compound belonging to the … Tavaborol
Products Echinocandins are commercially available as infusion preparations. Caspofungin was the first representative from this group to be approved in 2001, and in many countries in 2002. Structure and properties Echinocandins are semisynthetic agents derived from fermentation products of various fungi. These include , and F-11899 They are synthetic lipopeptides with a complex chemical structure … Echinocandine
Products Econazole is commercially available as a cream, powder, pump spray, vaginal cream, and vaginal suppository (Pevaryl, Gyno-Pevaryl, Pevisone + triamcinolone acetonide). The active ingredient has been approved in many countries since 1974. Structure and properties The imidazole derivative econazole (C18H15Cl3N2O, Mr = 381.7 g/mol) is a white powder that is practically insoluble in water. … Econazole
Products Voriconazole is commercially available as film-coated tablets, powder for the preparation of an infusion solution, and powder for the preparation of a suspension (Vfend, generics). It has been approved in many countries since 2002. Structure and properties Voriconazole (C16H14F3N5O, Mr = 349.3 g/mol) exists as a white powder that is very sparingly soluble in … Voriconazole
Products Sertaconazole is commercially available as a cream (Zalain). The drug is not available in many countries. Structure and properties Sertaconazole (C20H15Cl3N2OS, Mr = 437.8 g/mol) is present in drugs as sertaconazole nitrate, a white crystalline powder that is practically insoluble in water. Effects Sertaconazole (ATC D01AC14) is antifungal Indications Fungal skin infections
Products Micafungin is commercially available as a powder for the preparation of an infusion solution (Mycamine). It was approved in many countries in 2012. Structure and properties Micafungin (C56H70N9NaO23S, Mr = 1292.3 g/mol) is a complex molecule obtained as a derivative of a fermentation product of the fungus F-11899. It is present in the drug … Micafungin
Products Miconazole is available as a cream, miconazole mouth gel and shampoo, and commercially (e.g., Daktarin). It has been approved in many countries since 1972. This article refers to external therapy. See also under miconazole mouth gel and miconazole for nail fungus. The nail tincture for nail fungus treatment is no longer marketed in many … Miconazole
Products Miconazole was commercially available for the treatment of nail fungus as a tincture (Daktarin). The drug was approved in many countries since 1981. It was discontinued from distribution in 2020. Structure and properties Miconazole (C18H14Cl4N2O , Mr = 416.13 g/mol) is an imidazole derivative. It is not present in the tincture as the salt … Miconazole against Nail Fungus
