Products Olanzapine is commercially available as film-coated tablets, meltable tablets, and powder for solution for injection (Zyprexa, generics). It has been approved in the U.S. and EU since 1996 and in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Olanzapine (C17H20N4S, Mr = 312.4 g/mol) belongs to the thienobenzodiazepine … Olanzapine
Products Brexpiprazole was approved in the United States in 2015 and in the EU and many countries in 2018 in film-coated tablet form (Rexulti). Structure and properties Brexpiprazole (C25H27N3O2S, Mr = 433.6 g/mol) is structurally closely related to aripiprazole (Abilify, generics). Effects Brexpiprazole (ATC N05AX16) has antipsychotic properties. The effects are due to partial agonism … Brexpiprazole
Products Aripiprazole is commercially available in tablet, meltable tablet, syrup, solution for injection, and sustained-release injection suspension forms (Abilify, Abilify Maintena, generics). It has been approved in many countries since 2004 and in the United States since 2002. Generics entered the market in 2015. Also used is the prodrug aripiprazollauroxil (Aristada). Structure and properties Aripiprazole … Aripiprazole
Products Aripiprazollauroxil was newly approved in the United States in 2015 as a suspension for injection (Aristada). It has not yet been registered in many countries. Structure and properties Aripiprazollauroxil (C36H51Cl2N3O4, Mr = 660.7 g/mol) is the ester of -hydroxymethyl aripiprazole and lauric acid. Aripiprazollauroxil is a prodrug of aripiprazole (Abilify, generic). Unlike oral aripiprazole, … Aripiprazollauroxil
