Products Bisoprolol is commercially available in film-coated tablet form as a monopreparation (Concor, generic) and as a fixed combination with hydrochlorothiazide (Concor plus, generic). It has been approved in many countries since 1986. In 2016, a fixed combination with perindopril was approved (Cosyrel). Structure and properties Bisoprolol (C18H31NO4, Mr = 325.4 g/mol) is present in … Bisoprolol Effects and Side Effects
Products Carteolol is available in the form of extended-release eye drops (Arteoptic LA). Carteolol has been approved in many countries since 1984. Arteopilo, the combination with pilocarpine, is no longer marketed in many countries. Structure and properties Carteolol (C16H24N2O3, Mr = 292.4 g/mol) is a dihydroquinolinone and a racemate. It is present in drugs as … Carteolol
Products Bopindolol was commercially available in tablet form (Sandonorm). It had been approved in many countries since 1984 and was withdrawn from the market in August 2010. Currently, drugs containing bopindolol are no longer on the market in many countries. Another beta-blocker can be used as a substitute. Structure and properties Bopindolol (C23H28N2O3, Mr = … Bopindolol
Products Nebivolol is commercially available in tablet form as a monopreparation (Nebilet, generic, USA: Bystolic) and in combination with hydrochlorothiazide (Nebilet plus). The active ingredient has been approved in many countries since 1998. A fixed combination with valsartan is also available in some countries (Byvalson). Structure and properties Nebivolol (C22H25F2NO4, Mr = 405.4 g/mol) has … Nebivolol
Products Propranolol is approved for the treatment of hemangioma in the form of an oral solution (hemangiol). The drug goes on sale in many countries in November 2014. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. It is a racemate. Effects … Propranolol (Hemangioma)
Products Propranolol is commercially available in tablet, sustained-release capsule, and solution forms (Inderal, generic, hemangiol). It has been approved in many countries since 1965. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. Propranolol is a racemate. The -enantiomer is predominantly active. … Propranolol
Products Timolol is commercially available in the form of eye drops and as an eye gel. In addition to the original Timoptic, generics and various fixed combinations with other antiglaucomatous agents are also commercially available (brinzolamide, brimonidine, dorzolamide, travoprost, latanoprost). Timolol has been approved in many countries since 1978. See also under timolol gel (hemangioma). … Timolol
Products Esmolol is commercially available as an injection and infusion solution (Brevibloc, generic). It has been approved in many countries since 1990. Structure and properties Esmolol (C16H25NO4, Mr = 295.4 g/mol) is present in drugs as esmolol hydrochloride, a racemate and a white crystalline powder that is highly soluble in water. It is rapidly biotransformed … Esmolol
Products Celiprolol is commercially available in the form of film-coated tablets (Selectol). It has been approved in many countries since 1987. Structure and properties Celiprolol (C20H34ClN3O4, Mr = 415.95 g/mol is a racemate and is present in drugs as celiprolol hydrochloride, a white to pale yellow crystalline powder that is readily soluble in water. Effects … Celiprolol
Products Betaxolol is commercially available in the form of eye drops (Betoptic S). It has been approved in many countries since 1995. Structure and properties Betaxolol is present in drugs as betaxolol hydrochloride and racemate (C18H30ClNO3, Mr = 343.9 g/mol), a white crystalline powder that is very soluble in water. The enantiomer levobetaxolol is also … Betaxolol
Products Pindolol was commercially available in tablet form (Visken). It had been approved in many countries since 1969. Furthermore, a fixed combination with clopamide was available (Viskaldix). Structure and properties Pindolol (C14H20N2O2, Mr = 248.3 g/mol) is an indole derivative and a racemate. It exists as a white crystalline powder that is practically insoluble in … Pindolol
Products Levobunolol is commercially available in the form of eye drops (Vistagan). It has been approved in many countries since 1987. Structure and properties Levobunolol (C17H25NO3, Mr = 291.4 g/mol) is a dihydronaphthalinone and the -enantiomer of bunolol, which is significantly more potent than the -enantiomer. In pharmaceuticals, it is present as levobunolol hydrochloride. Effects … Levobunolol
