Products In many countries, drugs containing ergotamine are currently no longer on the market. The active ingredient was available in tablet form in combination with caffeine, among other products (Cafergot), but was withdrawn from the market in 2014. Products containing ergotamine were first launched in the 1920s (Gynergen). Structure and properties Ergotamine (C33H35N5O5, Mr = … Ergotamine
Products The marketing of medicinal products containing dihydroergotamine has been discontinued in many countries (e.g., Dihydergot tablets and nasal spray, Ergotonin, Effortil plus, Old Tonopan, and others). The approval of Dihydergot tablets was cancelled on February 1, 2014, because the benefits no longer outweighed the potential risks, according to drug regulators. Structure and properties Dihydroergotamine … Dihydroergotamine
Products Codergocrine was commercially available in tablet form, as a dropper solution, and as a solution for injection (Hydergin). It had been approved in many countries since 1949. Structure and properties Codergocrine is present in drugs as codergocrine mesilate, a white to yellowish powder that is sparingly soluble in water. It is a mixture of … Codergocrine
Products Methylergometrine is commercially available as a solution for injection (Methergin). Distribution of the drops was discontinued in 2011 and that of the dragées in 2018. Structure and properties Methylergometrine (C20H25N3O2, Mr = 339.4 g/mol) is a semisynthetic derivative of the natural alkaloid ergometrine. It is present in the drug as methyl ergometrine maleate. Effects … Methylergometrine
