Splenomegaly (Enlargement of the Spleen): Complications

The following are the most important diseases or complications that may be contributed to by splenomegaly (splenomegaly):

Blood, blood-forming organs – Immune system (D50-D90).

  • Hypersplenism – complication of splenomegaly; leads to increase in functional capacity beyond what is necessary; as a result, there is excessive elimination of erythrocytes (red blood cells), leukocytes (white blood cells), and platelets (thrombocytes) from peripheral blood, resulting in pancytopenia (synonym: tricytopenia; decrease in all three cell series in the blood).