Paragar Emulsion

Products Paragar Emulsion was approved in many countries in 1966. In 2018, its distribution was discontinued and the drug subsequently received a new composition with the active ingredient macrogol 3350 (new: Paragar Macrogol, powder for the preparation of a solution for oral use). Paragol with kerosene oil, for example, can also be used as a … Paragar Emulsion

Kerosene as a Laxative

Products Kerosene is commercially available as an emulsion (Paragol N) and gel (Lansoyl). Paragar is no longer sold. In pharmacies or drugstores, the kerosene oil emulsion PH can be produced or thick kerosene PhEur can be dispensed as open goods. The corresponding manufacturing specification for kerosene oil emulsion can be found in Pharmacopoea Helvetica. Structure … Kerosene as a Laxative

Lactitol

Products Lacitol is commercially available as a powder in sachets and as a syrup (Importal). It has been approved in many countries since 1985. Structure and properties Lactitol is present in drugs as lactitol monohydrate (C12H24O11 – H2O, Mr = 362.3 g/mol). Lactitol monohydrate is a white crystalline powder that is very soluble in water. … Lactitol

Lactulose: Role in Diet

Background Unlike lactose (milk sugar), lactulose does not occur naturally, except in very small amounts in heated milk, as a product of isomerization from lactose. The production of lactulose from lactose was first described in 1930. The sugar attracted interest in 1956 when Petuely demonstrated an increase in the number of lactobacilli in the stool … Lactulose: Role in Diet

Plecanatide

Products Plecanatide was approved in the United States in 2017 in film-coated tablet form (Trulance). Plecanatide is not currently approved in many countries. Structure and properties Plecanatide (C65H104N18O26S4, Mr = 1681.9 g/mol) is a 16 amino acid peptide derived from uroguanylin. It contains two disulfide bridges. Plecanatide exists as an amorphous white powder that is … Plecanatide

Castor Oil: Medicinal Uses

Products Castor oil is available in pharmacies and drugstores as an open product. Specialty retailers can order it from Hänseler, for example. Extraction Virgin castor oil is the fatty oil obtained from the seeds of the miracle tree L. of the spurge family by cold pressing. A suitable antioxidant may be added. Refined castor oil … Castor Oil: Medicinal Uses

Sterculia Gum (Karaya)

Products Sterculia gum is commercially available as granules for oral use (e.g., Colosan mite, Normacol). The gum is also known as karaya gum. Structure and properties Sterculia gum is obtained from the exudate from the trunks and branches of trees of the genus (e.g. ) of the mallow family. These are native to India and … Sterculia Gum (Karaya)

Dulcolax®

Dulcolax® is a drug containing the active ingredient bisacodyl and belongs to the group of so-called laxatives. A laxative is a drug that can regulate intestinal movements and is thus used to treat constipation. Colloquially, Dulcolax® thus belongs to the group of “laxatives“. Dulcolax® is available in various dosage forms. It can be taken orally … Dulcolax®

Lactulose

Lactulose is a medicine used in the form of a syrup for laxative purposes. Fields of application Constipation, which cannot be sufficiently influenced by dietary changes etc. For diseases of the intestine etc. Prophylaxis and therapy of portocaval encephalopathy (liver disease) Contraindications The lactulose syrup must not be used for Hypersensitivity to lactulose or other … Lactulose

Overdose | Lactulose

Overdose If too much lactulose is ingested, nausea, vomiting, diarrhea and loss of water and electrolytes may occur. These manifestations of the drug may then have to be treated with other drugs and should be under the supervision of a doctor. The doctor will then decide on the measures necessary to treat the symptoms. If … Overdose | Lactulose