Xylometazoline

Products Xylometazoline is commercially available in the form of nasal sprays and as nasal drops (Otrivin, generics, combination products, for example with dexpanthenol). It was developed at Ciba and has been approved in many countries since 1958. Structure and properties Xylometazoline is present in drugs as xylometazoline hydrochloride (C16H24N2 – HCl, Mr = 280.8 g/mol), … Xylometazoline

Oxymetazoline

Products Oxymetazoline is commercially available in the form of nasal drops and as a nasal spray with or without a preservative (Nasivin, Vicks Sinex). It has been approved in many countries since 1972. Oxymetazoline is also used to treat rosacea; see oxymetazoline cream. Structure and properties Oxymetazoline (C16H24N2O, Mr = 260.4 g/mol) is present in … Oxymetazoline

Tuaminoheptane

Products Tuaminoheptane is commercially available in combination with acetylcysteine in the form of a nasal spray (rinofluimucil). It has been approved in many countries since 1990. Structure and properties Tuaminoheptane (C7H17N, Mr = 115.2 g/mol) is a primary amine. Effects Tuaminoheptane (ATC R01AA11, ATC R01AB08) has sympathomimetic, vasoconstrictor, and decongestant properties. It facilitates breathing and … Tuaminoheptane