Products Marbofloxacin is commercially available in tablet form and as an injection solution for animals, among other products. It has been approved in many countries since 2000. Structure and properties Marbofloxacin (C17H19FN4O4, Mr = 362.4 g/mol) is a fluoroquinolone. Effects Marbofloxacin (ATCvet QJ01MA93) has bactericidal properties. The effects are due to inhibition of DNA gyrase. … Marbofloxacin
Products Maropitant is commercially available as a solution for injection and in tablet form as a veterinary drug (Cerenia). It has been approved in many countries since 2008. Structure and properties Maropitant (C38H50N2O9, Mr = 678.8 g/mol) Effects Maropitant (ATCvet QA04AD90) has antiemetic properties. The effects are due to inhibition of substance P binding to … Maropitant
Products Tepoxaline is commercially available in tablet form (Zubrin). It has been approved in many countries since 2003. Structure and properties Tepoxaline (C20H20ClN3O3, Mr = 385.8 g/mol) is a pyrazole derivative. Effects Tepoxaline (ATCvet QM01AE92) is analgesic and anti-inflammatory. The properties are based on inhibition of prostaglandin synthesis. The effects are mainly mediated by the … Tepoxaline
Products Pradofloxacin is commercially available in the form of tablets for dogs and cats. It has been approved in many countries since 2012. Structure and properties Pradofloxacin (C21H21FN4O3, Mr = 396.4 g/mol) is a fluoroquinolone. Effects Pradofloxacin (ATCvet QJ01MA97) has bactericidal properties. The effects are due to inhibition of bacterial DNA gyrase and topoisomerase IV. … Pradofloxacin
Products Sarmazenil is commercially available as a solution for injection (Sarmasol). It has been approved in many countries since 1993. Structure and properties Sarmazenil (C15H14ClN3O3, Mr = 319.7 g/mol) Effects Sarmazenil (ATCvet QV03AB91) abolishes the effects of benzodiazpines. Indications To reverse the effects of benzodiazepines, especially climazolam in dogs.
Products Sarolaner was approved in the EU in 2015 and in many countries in 2017 in the form of chewable tablets for dogs (Simparica). Structure and properties Sarolaner (C23H18Cl2F4N2O5S, Mr = 581.4 g/mol) belongs to the isoxazoline group. Effects Sarolaner (ATCvet QP53BX06) has antiparasitic properties against fleas, ticks, and mites. Indications For the treatment of … Sarolan
Products Imepitoin is commercially available in tablet form (Pexion). It has been approved in many countries since 2013. Structure and properties Imepitoin (C13H14ClN3O2, Mr = 279.7 g/mol) is a morpholine and imidazolone derivative. It is structurally unrelated to the benzodiazepines. Effects Imepitoin (ATCvet QN03AX90) has antiepileptic properties. Its effects are due to partial agonism with … Imepitoin
Products Imidapril is registered as a powder for oral solution (Prilium). It has been approved in many countries since 2004. Imidapril has also been used in humans, but no human medicines are currently registered in many countries (Tanatril). Structure and properties Imidapril (C20H27N3O6, Mr = 405.4 g/mol) is a prodrug and is biotransformed by ester … Imidapril
Products Imidocarb is commercially available as a solution for injection (Carbesia). It has been approved in many countries since 2011. Structure and properties Imidocarb (C19H20N6O, Mr = 348.4 g/mol) is a substituted carbanilide. It is present in drugs as imidocarbdipropionate. Effects Imidocarb (ATCvet QP51AE01) has antiparasitic properties against ssp. Indications For prevention and treatment of … Imidocarb
Active substances Flea medications are commercially available in the form of solutions for application (spot-on), tablets, as suspensions, shampoos, sprays, injectables, flea collars and foggers, among others. 1. insecticides kill fleas directly and are sometimes effective for weeks: pyrethroids and pyrethrins: Permethrin (eg Exspot) – not suitable for cats! Neonicotinoids: Imidacloprid (Bayvantage). Nitenpyram (Capstar) Phenylpyrazoles: … Flea Remedy
Products Florfenicol is commercially available as a solution for injection for animals. It has been approved in many countries since 1996. Structure and properties Florfenicol (C12H14Cl2FNO4S, Mr = 358.2 g/mol) is structurally closely related to chloramphenicol. Effects Florfenicol (ATCvet QJ01BA90) has bacteriostatic properties. The effects are due to inhibition of bacterial protein synthesis. Indications For … Florfenicol
Products Flubendazole is commercially available as a paste, drug premix, and chewable tablets for animals. It has been approved in many countries since 1984. Human drugs are not currently registered. Structure and properties Flubendazole (C16H12FN3O3, Mr = 313.3 g/mol) is a fluorinated benzimidazole derivative. It is a white powder that is practically insoluble in water … Flubendazole
