General measures Adjustment of existing underlying diseases to optimal levels (see “Drug therapy“). Increase physical activity to 2.5-5 hours per week of moderate aerobic exercise or 1.25-2.5 hours per week of intense aerobic exercise. Aim for normal weight! Determination of BMI (body mass index, body mass index) or body composition by means of electrical impedance … Hypertriglyceridemia: Therapy
Medical history (history of illness) represents an important component in the diagnosis of hyperlipoproteinemia (hypertriglyceridemia). Family History Is there a frequent occurrence of dyslipidemia in your family? Are there any hereditary diseases in your family? Social history Is there any evidence of psychosocial stress or strain due to your family situation? Current medical history/systemic history … Hypertriglyceridemia: Medical History
Endocrine, nutritional, and metabolic diseases (E00-E90). Obesity (obesity). Acromegaly – increase in size of body end limbs due to increased presence of growth hormone after completion of growth. Cushing’s disease/Cushing’s syndrome – disease in which a tumor in the ACTH-producing cells of the pituitary gland produces too much ACTH, resulting in increased stimulation of the … Hypertriglyceridemia: Or something else? Differential Diagnosis
Care should be taken to The intake of saturated fatty acids, such as in meat and sausages, and cholesterol, especially in eggs and animal products such as brain, liver and kidney, is reduced In addition, the intake of simple sugars dextrose, lactose and fructose should also be reduced
The following are the most important diseases or complications that may be contributed to by hypertriglyceridemia: Eyes and ocular appendages (H00-H59). Visual disturbances Endocrine, nutritional and metabolic diseases (E00-E90). Somatopause, premature – due todegradation of triglycerides to free fatty acids (FA) and glycerol → suppression of growth hormone secretion (synonyms: somatotropic hormone (STH), somatotropin) as … Hypertriglyceridemia: Complications
Within the framework of micronutrient medicine (vital substances), the following vital substances (micronutrients) are used for prevention: Omega-3 fatty acid docosahexaenoic acid. Omega-3 fatty acid eicosapentaenoic acid Omega-6 fatty acid gamma-linolenic acid Omega-6 fatty acid linoleic acid Secondary plant compounds daidzein, genistein and glycitein In the context of micronutrient medicine (vital substances), the following vital … Hypertriglyceridemia: Micronutrient Therapy
To prevent hypertriglyceridemia, attention must be paid to reducing individual risk factors. Behavioral risk factors Diet Increased intake of: Calories (as fat or rapidly metabolized carbohydrates). Triglycerides (neutral fats, dietary fat) – animal fats. Trans fatty acids (10-20 g/day; e.g., baked goods, chips, fast food products, convenience foods, fried foods such as French fries, breakfast … Hypertriglyceridemia: Prevention
The following symptoms and complaints may indicate hypertriglyceridemia: Eruptive xanthomas (small yellowish-white skin lesions). Recurrent pancreatitis (inflammation of the pancreas) in childhood* . Acute pancreatitis (when triglyceride levels are > 1,000 mg/dl; upper abdominal symptoms with extreme pain). Hepatospenomegaly/enlargement of liver and spleen (anemia/anemia, thrombocytopenia/lack of platelets)* . Early atherosclerosis (arteriosclerosis, hardening of the arteries). … Hypertriglyceridemia: Symptoms, Complaints, Signs
Therapy for hyperlipoproteinemia (hypertriglyceridemia) is based on the following pillars: Secondary prevention, that is, reduction of risk factors. Drug therapy Micronutrient therapy (vital substances) Further therapy (lifestyle change, etc.) The treatment modality for hyperlipoproteinemia depends on the level of LDL measured and the risk factors that the individual has: Risk group LDL target value in … Hypertriglyceridemia: Treatment
Hypertriglyceridemia refers to an elevated triglyceride content of the blood serum. Naturally occurring fats consist predominantly of triacylglycerols, which are also called triglycerides (TG) or neutral fats. In addition, there are small amounts of mono- and diacylglycerols. Triglycerides serve as energy stores. The nearly 12 kg of triglycerides that a normal-weight person stores in adipose … Triglycerides
Pathogenesis (disease development) There are several factors that can lead to hypertriglyceridemia: Genetic burden (see below). Excessive stress due to lifestyle and diet Diseases Drug side effects Excessive alcohol consumption (> 30 g/day) inhibits the oxidation of fatty acids in the liver. As a result, more fats are synthesized (→ steatosis hepatis/fatty liver) and released, … Hypertriglyceridemia: Causes
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye) [xanthomas – small yellowish-white skin lesions]. Auscultation (listening) of the heart [early atherosclerosis (arteriosclerosis, hardening of the arteries) → … Hypertriglyceridemia: Examination
