Metabolic Alkalosis: Consequential Diseases

The following are the major diseases or complications that may be contributed to by metabolic (metabolic-related) alkalosis: Respiratory system (J00-J99) Cor pulmonale – right heart enlargement due to lung structural changes. Cardiovascular system (I00-I99) Cardiac arrhythmias Heart failure Psyche – nervous system (F00-F99; G00-G99) Disorders of consciousness Coma Symptoms and abnormal clinical and laboratory findings, … Metabolic Alkalosis: Consequential Diseases

Metabolic Alkalosis: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; furthermore: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye). Auscultation (listening) of the heart [cardiac arrhythmia]. Auscultation of the lungs Palpation (palpation) of the abdomen (abdomen) (tenderness?, knocking … Metabolic Alkalosis: Examination

Metabolic Alkalosis: Lab Test

Acid-base status PH ↑ Bicabonate (HCO3-) current ↑ Bicarbonate standard ↑ Basenexcess (base excess) – normal, increased with partial compensation. Blood carbon dioxide partial pressure (pCO2) – normal [after partial compensation by decreased respiration – increased (hypercapnia)] Other possible examinations Blood oxygen partial pressure (pO2) – unchanged. Oxygen saturation (SpO2) Acidoses and alkaloses Acidosis Alkalosis … Metabolic Alkalosis: Lab Test

Metabolic Alkalosis: Drug Therapy

Therapeutic target Restoration of a balanced acid-base balance. Therapy recommendations Metabolic acidosis can be poorly compensated by the body, since this would require a reduction in respiration, which is only possible to a limited extent, since the body must continue to be supplied with sufficient oxygen. Treatment of chloride-sensitive alkalosis (urine chloride < 10 mmol/l). … Metabolic Alkalosis: Drug Therapy

Metabolic Alkalosis: Diagnostic Tests

Optional medical device diagnostics-depending on the results of history, physical examination, laboratory diagnostics, and obligatory medical device diagnostics-for differential diagnostic clarification Abdominal ultrasonography (ultrasound examination of the abdominal organs) – for suspected intra-abdominal changes, for example, due to renal artery stenosis (renal artery stenosis) or hormone-producing tumors. Electrocardiogram (ECG; recording of the electrical activity of … Metabolic Alkalosis: Diagnostic Tests

Metabolic Alkalosis: Medical History

Medical history (history of illness) represents an important component in the diagnosis of metabolic (metabolic-related) alkalosis. Family history Are there any hereditary diseases in your family? Social anamnesis Current medical history/systemic medical history (somatic and psychological complaints). Have you noticed any sensory disturbances? Have you noticed any muscle spasms? Have you noticed any cardiac arrhythmias? … Metabolic Alkalosis: Medical History

Metabolic Alkalosis: Or something else? Differential Diagnosis

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). Congenital renal artery stenosis – narrowing of the renal artery(s) leading to hypertension (high blood pressure). Congenital chloride diarrhea – genetic disease with autosomal recessive inheritance; caused by chloride malabsorption; characterized by osmotic watery diarrhea (diarrhea) beginning after birth, accompanied by alkalosis. Liddle syndrome – very rare genetic … Metabolic Alkalosis: Or something else? Differential Diagnosis

Metabolic Alkalosis: Causes

Pathogenesis In metabolic (metabolic) alkalosis, the blood pH has risen above 7.45 because of an increase in bicarbonate (see below for addition alkalosis) or loss of hydrogen ions (see below for subtraction alkalosis). Possible causes of metabolic alkalosis are addition alkalosis and subtraction alkalosis: Metabolic alkalosis can result from either increased uptake or production of … Metabolic Alkalosis: Causes

Metabolic Alkalosis: Therapy

General measures Avoidance of chewing tobacco Refraining from using the medicinal plant black cohosh (recommended as a supportive measure for menopausal symptoms in women, such as hot flashes and night sweats) Review of permanent medication due topossible effect on the existing disease. Nutritional medicine Nutritional counseling based on nutritional analysis Nutritional recommendations according to a … Metabolic Alkalosis: Therapy