Optic Neuritis: Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests. Small blood count Differential blood count* Inflammatory parameters – CRP (C-reactive protein) or ESR* (erythrocyte sedimentation rate). Electrolytes (blood salts)* – calcium, sodium, potassium. Fasting glucose* (fasting blood glucose). Alanine aminotransferase* (ALT, GPT) Creatinine kinase (CK)* LDL* Uric acid* Vitamin B12* CSF examinations* (examination of … Optic Neuritis: Test and Diagnosis

Optic Neuritis: Drug Therapy

According to S2e guidelines, glucocorticosteroid therapy should be given for typical optic neuritis: In adults: 500-1,000 mg i. v. as infusion or oral methylprednisolone per day for 3-5 days. The indication for administration of single doses above 0.5 g should be made critically because of possible hepatotoxicity (liver-damaging effect), at least in patients over 50 … Optic Neuritis: Drug Therapy

Optic Neuritis: Medical History

Medical history represents an important component in the diagnosis of optic neuritis (optic neuritis). Family history Is there a frequent history of neurologic disease in your family? Are there frequent autoimmune diseases in your family? Social history Is there any evidence of psychosocial stress or strain due to your family situation? Current medical history/systemic history … Optic Neuritis: Medical History

Optic Neuritis: Or something else? Differential Diagnosis

Eyes and ocular appendages (H00-H59). Anterior sham optic neuropathy-acute occlusion of an ophthalmic artery supplying the optic nerve in the Zinn-Haller vascular cortex; also called ocular infarction; clinical presentation: acute onset; no eye movement pain, but diffuse eye pain possible; usually little improvement; ophthalmologic findings: papilledema (congestive papillae): always in the acute stage. Leber’s hereditary … Optic Neuritis: Or something else? Differential Diagnosis

Optic Neuritis: Complications

The following are the most important diseases or complications that can be caused by optic neuritis (optic neuritis): Eyes and eye appendages (H00-H59). Blindness of the affected eye (3% of cases). Visual impairment (visual acuity/visual acuity ≥ 1 in 11% of cases). Psyche – nervous system (F00-F99; G00-G99) Multiple sclerosis (MS) – approximately 50% of … Optic Neuritis: Complications

Optic Neuritis: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin and mucous membranes Aisle Tremor (shaking) Extremities Ophthalmological examination [due tosymptoms: Eye movement pain: visual disturbances are usually preceded by pain in the eye region (92% of patients), … Optic Neuritis: Examination

Optic Neuritis: Diagnostic Tests

Obligatory medical device diagnostics. Eye examination Slit-lamp examination (slit-lamp microscope; viewing of the eyeball under appropriate illumination and high magnification; in this case: Viewing of the anterior and middle sections of the eye). Ophthalmoscopy (ophthalmoscopy; examination of the central fundus) – to diagnose optic neuritis [paille usually appears sharp; may be mild papilledema (one-third of … Optic Neuritis: Diagnostic Tests

Optic Neuritis: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate optic neuritis (optic neuritis): Eye movement pain (eye movement pain; bulbar movement pain; bulbar pain (pressure, movement); 92% of patients). Visual loss (visual deterioration) (onset: within hours to days) [visual impression: Blurred vision to complete loss of visual acuity (vision loss). Disturbed color perception (colors are perceived as … Optic Neuritis: Symptoms, Complaints, Signs

Optic Neuritis: Causes

Pathogenesis (development of disease) Typical optic neuritis occurs either in the setting of multiple sclerosis (majority of cases) or idiopathically (with no apparent cause). It involves a T-cell-, B-cell-, and microglia-mediated immune reaction against optic nerve tissue. Atypical optic neuritis may result from the following disease mechanisms: As a manifestation of an autoimmune disease, eg. … Optic Neuritis: Causes