Products
Heparin sodium is applied primarily as a gel or ointment (eg, HepaGel, Lioton, Demovarin, combination products). This article refers to topical therapy. Heparin sodium is also injected parenterally.
Structure and properties
Heparin sodium is the sodium salt of a sulfated glycosaminoglycan found in mammalian tissues. It is obtained from the intestinal mucosa of pigs, among other sources. Heparin sodium exists as a white powder that is readily soluble in water.
Effects
Heparin sodium (ATC C05BA03) has antithrombotic, anti-inflammatory, analgesic, and resorptive properties. Heparin binds to antithrombin III, and the resulting complex inactivates various clotting factors, inhibiting blood clotting.
Indications
- Complaints associated with varicose veins, such as pain, heaviness, and swelling
- Blunt sports and accident injuries such as bruises, contusions and strains.
- Bruise
- Pain of the muscles and tendons
- Scar care
- Superficial phlebitis
- For the aftercare of sclerotherapy
- Venous thrombosis (supportive therapy).
Dosage
According to the professional information. Medicines are usually applied three or more times a day. Use only on intact skin. The drugs should not get into the eyes or on mucous membranes.
Contraindications
- Hypersensitivity
- Heparin-induced/associated thrombocytopenia.
For complete precautions, see the drug label.
Interactions
Drug-drug interactions with systemic anticoagulants are considered unlikely.
Adverse effects
Rarely, local reactions and allergic reactions may occur.
