Products Enoxaparin is commercially available as a solution for injection (Clexane). It has been approved in many countries since 1988. Biosimilars were released in the EU in 2016 and in many countries in 2020 (Inhixa). Structure and properties Enoxaparin is present in the drug as enoxaparin sodium, the sodium salt of a low-molecular-weight heparin (LMWH) … Enoxaparin
Products Nadroparin is commercially available as a solution for injection (Fraxiparine, Fraxiforte). It has been approved in many countries since 1988. Structure and properties Nadroparin is present in the drug as nadroparin calcium. It is the calcium salt of a low-molecular-weight heparin obtained by depolymerization of heparin from the intestinal mucosa of pigs using nitrous … Nadroparin
Products Insulins are primarily commercially available in the form of clear injection solutions and turbid injection suspensions (vials, cartridges for pens, ready-to-use pens). In some countries, inhalation preparations are also available. However, these are an exception. Insulins should be stored in a refrigerator at 2 to 8°C (see under Refrigerated Storage). They must not be … Insulins
Products Heparin sodium is applied primarily as a gel or ointment (eg, HepaGel, Lioton, Demovarin, combination products). This article refers to topical therapy. Heparin sodium is also injected parenterally. Structure and properties Heparin sodium is the sodium salt of a sulfated glycosaminoglycan found in mammalian tissues. It is obtained from the intestinal mucosa of pigs, … Heparin Sodium
Products Heparin–Calcium is commercially available as an injectable (Calciparine). It has been approved in many countries since 1973. Structure and properties Heparin calcium is the calcium salt of a sulfated glycosaminoglycan found in mammalian tissues. It is derived from the intestinal mucosa of pigs. Heparin calcium exists as a white powder that is readily soluble … Heparin-Calcium
Products Protamine is commercially available as an injectable. It has been approved in many countries since 1949. Structure and properties Protamine is present in the drug as protamine hydrochloride. It consists of the hydrochlorides of basic peptides with a deep molecular mass and a high arginine content, obtained from sperm or roe of fish (mostly … Protamine
Products Certoparin was commercially available as a solution for injection (Sandoparin, off label). It was approved in many countries from 1989 to 2018. Structure and properties Certoparin is present in drugs as certoparin sodium. Effects Certoparin (ATC B01AB01) has antithrombotic properties. The effects are primarily due to inhibition of coagulation factor Xa by complexation with … Certoparin
