Liver values in hepatitis
As a rule, if liver damage is suspected in the context of hepatitis, the liver values GOT, GPT and GGT are determined together with other values not related to the liver. However, the change in liver values also depends on the type and severity of the hepatitis. Depending on the type of hepatitis (hepatitis A-E), it can be strong or weak and show acute or chronic progression. In acute, severe viral hepatitis, liver values such as GGT rise faster and more strongly than in chronic, less pronounced viral hepatitis. You will find all information about the disease hepatitis in the following article: Hepatitis – Everything you should know
Liver values in liver cirrhosis
In the case of liver cirrhosis, various values are determined to confirm the diagnosis and to monitor the course of the disease. In addition to the typical liver values GOT, GPT, GLDH, bilirubin and GGT, which are elevated in liver cirrhosis, other parameters can be determined. Cholinesterase, various coagulation factors and other liver products are among the determined values. These are often not the typical liver values, as they are either not indicative or not specific for the liver in many cases. They are also usually lowered rather than increased, as the liver’s synthesis capacity decreases as the disease progresses.
Liver values for fatty liver
The liver values in a fatty liver depend on the origin of the disease. If the disease does not occur in the context of a chronic alcohol abuse, then in addition to the typically elevated gamma-GT, the transaminases are also elevated. The transaminases include GOT and GPT.
The de ritis quotient is the ratio between AST and ALT or GOT and GPT. In fatty liver, which is the result of a chronic alcohol abuse, the gamma-GT is typically also increased. If a pure fatty liver has already developed into a fatty liver with inflammation, the GOT, GPT, GLDH and alkaline phosphatase are also elevated.
In addition, the synthesis performance can already be reduced, which can also be proven in the laboratory. The de ritis quotient is usually above 1. By determining the value of CDT, the alcohol consumption can be estimated.
