Parasitic Worms (Helminths), Helminthiasis: Drug Therapy

Therapeutic target

  • Elimination of the worms

Therapy recommendations

  • Anthelmintics (drugs against worm diseases).
Trunk Family [name of disease] Agents Special features
Cestodes (tapeworms)
Cyclophyllidae Praziquantel
Echinococcus[Echinococcosis.] AlbendazoleMebendazole for alveolar echinococcosis. For E. multilocularis, lifelong therapy
Hymenolepidae NiclosamidePraziquantel
Pseudophyllidae PraziquantelNiclosamide
Nematodes (nematodes)
Ancylostomatidae AlbendazoleMebendazolePyrantelembonate (N. americanus).
Angiostrongylus AlbendazoleMebendazoleLevimazoleThiabendazole
Ascarididae (roundworms) AlbendazoleMebendazole In anisakis simplex, often self-healing
Enterobius vermicularis (pinworm) AlbendazoleMebendazole
Filariae Diethylcarbamazingif necessary with albendazole,doxycycline ivermectin.
Oxyuridae (pinworms) AlbendazoleMebendazolePyrantelembonatePyrviniumembonate Therapeutic success rates up to >90%.
Rhabditidae AlbendazoleIvermectinMebendazoleThiabendazole
Trichinella(Trichinella) [Trichinellosis]. AlbendazoleMebendazole Prednisolone if necessary for severe myositis/myocarditis
Trichuridae AlbendazoleMebendazole
Trichuris trichiura (whipworm) AlbendazoleMebendazole
Spiruridae MetronidazoleThiabenzole The most important measure is mechanical removal of the worm
Strongyloides stercoralis (dwarf nematode). ThiabendazolIvermectin
Trematodes (sucking worms)
Intestinal fluke Praziquantel Single dose
Liver fluke BithionolPraziquantel/Albendazole 2nd choice onlyTriclabenazole
Lung Leech Praziquantel
Schistosomatidae[schistosomiasis; schistosomiasis] Praziquantel

See also under “Further therapy“.