The following are the most important diseases or complications that can be caused by penile carcinoma (penile cancer):
Neoplasms and tumor diseases (N00-N99).
- Metastasis (“formation of daughter tumors”), especially to the following organs:
- Lymphogenic (lymph nodes; relatively early metastasis).
- Hematogenous (“in the bloodstream”) metastasis to lungs, liver, bones or CNS.
Highest metastatic tendency: sarcomatoid, pseudoglandular and basaloid carcinomasLowest metastatic tendency: verrucous and warty subtypes of penile squamous cell carcinoma.
- Recurrence (recurrence) of the disease (peak incidence: -2 years).
Prognostic factors
- PT stage (depth of infiltration), malignancy grade, and microvascular invasion (lymphatic and venous) are the most important criteria for lymph node metastasis
