Peripheral Artery Disease: Test and Diagnosis

1st-order laboratory parameters-obligatory laboratory tests.

  • Small blood count
  • Inflammatory parameters – CRP (C-reactive protein).
  • Urine status
    • Urine pH
    • Total protein
    • Glucose and ketone bodies (provide information about glucose metabolism).
    • Bilirubin (indicating cholestasis/liver damage) and urobilinogen, gives indication of hemolysis (destruction of red blood cells) as well as liver damage.
    • Nitrite (may indicate an infection of nitrite-forming bacteria).
  • Fasting glucose (fasting blood glucose).
  • HbA1c (long-term blood glucose value)
  • Renal parameters – urea, creatinine, cystatin C if necessary.
  • Total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides.
  • Homocysteine
  • Apolipoprotein B (Apo B; APOB) – blood sample taken after a food abstinence of circa 10-14 hours; Apo B is usually elevated in paVK.
  • Coagulation parameters – Quick value, PTT (partial thromboplastin time).
  • Fibrinogen (clotting factor I) – risk factor for thromboembolic events as well as coronary artery disease (CAD).

Pathological CRP and HbA1c serum levels correlate with the risk of developing peripheral arterial disease.