Pathogenesis (development of disease)
The exact pathogenesis of Perthes disease is not yet clear.
Several pathogenetic factors are discussed that may play a role:
- Subcritical vascular supply
- Constitution/skeletal retardation
- Multiple bone infarcts
There is then a local tissue destruction (necrosis) in the area of the epiphysis (joint end with bone core). The consequence is a disturbance of the ossification (ossification) of the femoral head.
