Prostaglandins at birth
One way to induce a birth is the administration of different prostaglandins. There are different ways of administering these. For example, prostaglandins can be applied locally in the form of a gel or administered as tablets (technical term: priming).
The onset of action (initiation of birth) usually takes two to three hours. As a result of the administration of prostaglandins, the cervix becomes more flexible and softer. Whether a gynaecologist should perform this method is often determined by the so-called bishop score (an assessment based on measurable anatomical factors such as the width of the cervix).
A small but relevant difference is the type of prostaglandin used. There are so-called prostaglandin E1 analogues and prostaglandin E2 analogues. One of the main differences between prostaglandin E1 and E2 analogues is that a prostaglandin E1 analogue (e.g. misoprostol) is usually applied orally, is less expensive and causes more frequent overstimulation of the uterus (also called labour storm). As a result, prostaglandin E1 is often perceived as the more unpleasant variant. In addition, it should not be used after surgery on the uterus.
Prostaglandins and eye drops
Prostaglandin analogues also have a field of application in ophthalmology. They are used to treat wide-angle glaucoma and increased intraocular pressure (glaucoma, glaucoma). Side effects, which are pointed out in the package insert, are local defensive reactions in the form of redness of the eye, pigmentation of the iris and changes in the area of the eyelashes (thickness, number, length).
It is not advisable to use these eye drops during pregnancy, as otherwise the birth could be induced early. Some patients also complain about side effects that affect the whole organism when taking certain medications. This can manifest itself in a lowered skin irritation threshold, rash (especially on the palms of the hands), sweating, anxiety, trembling, insomnia and increased dreaming.
