Pseudomembranous Enterocolitis: Therapy

General measures

  • Isolation measure, i.e. accommodation in single room (cohort isolation) with own wet room.
  • If necessary, cohort isolation for patients with the same pathogen type.
  • Wearing protective gowns / disposable gloves for close patient contact.
  • Careful hand hygiene (in addition to (in addition to hand disinfection washing hands with soap, as alcohol-based disinfectants do not have sufficient effect against spores).
  • Daily wipe disinfection of surfaces near the patient.
  • Use medical devices patient-related and disinfect after use.
  • Isolation measures should remain in place for up to 48 hours after the diarrhea has stopped
  • Review of permanent medication due topossible effect on the disease present.
    • Discontinuation of the antibiotic causing the disease: stopping antibiotic therapy leads to cessation of diarrhea in more than 20%.

Conventional non-surgical therapy methods

  • Fecal transplantation (microbiome transfer; duodenal infusion of feces/stools from healthy individuals or by colonoscopy (colonoscopy) or by enema) – for reconstruction of intestinal flora; indication: method of choice for multiple failures of drug recurrence or complicated recurrences (recurrence) of Clostridium difficile infection; ; Success rates are between 85-90% after one transfer and up to 100% after a second treatment.Frozen preparations have achieved equally good results as fresh stool samples in patients with recurrent Clostridium difficile infections.

Nutritional Medicine

  • Nutritional counseling based on nutritional analysis
  • Nutritional recommendations according to a mixed diet taking into account the disease at hand. This means, among other things:
    • Daily total of 5 servings of fresh vegetables and fruits (≥ 400 g; 3 servings of vegetables and 2 servings of fruits).
    • Once or twice a week fresh sea fish, i.e. fatty marine fish (omega-3 fatty acids) such as salmon, herring, mackerel.
    • High-fiber diet (whole grains, vegetables).
  • Observance of the following special dietary recommendations:
    • Avoid
      • Raw or inadequately heated, contaminated, and spoiled foods, such as raw milk, eggs and egg dishes, fish and seafood, and meat, especially poultry. Furthermore, these include:
        • Raw milk and products made from raw milk (e.g. raw milk cheese).
        • Raw or not sufficiently heated meat and minced meat.
        • Spreadable raw sausages (e.g. onion mettwurst, Teewurst “Braunschweiger Mettwurst”).
      • Contaminated drinking water
      • Food and food, such as potato and pasta salad, left for a long time in a warm environment or otherwise improperly stored.
      • Very fatty or cold foods
      • High amounts of unripe fruit
      • Allergy-causing foods, such as milk, egg, chocolate, yeast, nuts, cheese, fish, fruits, vegetables, in the presence of a food allergy.
    • In any case, adequate fluid and electrolyte replacement must be made to compensate for the high water loss in enteritis. In the elderly and infants or young children, an electrolyte powder may need to be used to prevent further complications.
  • Selection of appropriate food based on the nutritional analysis.
  • See also under “Therapy with micronutrients (vital substances)” – Taking a suitable dietary supplement.
  • Detailed information on nutritional medicine you will receive from us.