Salivary Stone Disease (Sialolithiasis): Drug Therapy

Therapeutic targets

• In case of bacterial infection: cure.
• Pain relief
• Relief of xerostomia (dry mouth)

Therapy recommendations

• Symptomatic therapy
  • Analgesia (analgesics/painkillers).
    • Nonacid analgesics: Paracetamol
    • Antipyretics (antipyretic drugs), if necessary.
    • If necessary, also antiphlogistics (anti-inflammatory drugs): acetylsalicylic acid (ASS), diclofenac, ibuprofen, indometacin.
• Antibiosis (antibiotic therapy).
  • Indications:
    • Acute bacterial sialadenitis
    • Chronic recurrent sialadenitis of the submandibular gland during the acute interval
    • Supportive curative to surgical intervention.
    • Endocarditis (endocarditis)-prone patients, regardless of the severity of infection.
    • Risk of exacerbation (significant worsening of symptoms) of a general disease.
    • Impaired immune defenses (eg, cytostatic or systemic corticosteroid therapy, immunosuppression), regardless of the severity of infection.
    • Postoperative persistent (continuing) inflammation despite adequate drainage (drainage of salivary fluid).
• Sialagoga (drugs that promote saliva production) – Via excitation of the parasympathetic nervous system, they lead to increased saliva production.