Side effect high blood pressure | Side effects of Diclofenac

Side effect high blood pressure

Diclofenac can also increase blood pressure. Inhibition of COX 1 leads to increased sodium retention in the kidney and thus to water reabsorption. The consequence is an increase in blood pressure. In addition, inhibition of COX 2 leads to reduced vasodilatation and this can also cause an increase in blood pressure.Diclofenac can therefore reduce the effect of blood pressure-lowering drugs such as ACE inhibitors.

Interaction with alcohol

Taking Diclofenac and drinking alcohol at the same time should be avoided. There are several reasons why this combination is not recommended. The risk of a stomach ulcer increases.

Liver and kidney damage may occur. In addition, the risk of a blood disposition increases. Taking Diclofenac and drinking alcohol at the same time can lead to unforeseeable short-term and long-term damage.

Blood picture changing effect

A rather rare side effect, but not without danger, is the effect of Diclofenac on the blood count. These occur mainly after long-term use and are usually not noticed by the patient. For this reason, it is important to test the blood of patients who have been taking Diclofenac regularly for a long time. People who take high doses of Diclofenac are particularly at risk. In addition, patients who already suffer from pre-existing blood disorders should pay special attention to regular blood tests.

How long do the side effects last?

With regard to the duration of side effects, a distinction must be made between short-term and long-term side effects. The short-term side effects such as sweating disappear when the medication is discontinued or when the fever is controlled. Most of the longer-term side effects only occur when Diclofenac is taken permanently.

In these cases, permanent restrictions may occur, for example on the kidneys or heart. Diclofenac should only be taken for a short time and in small amounts. If a permanent intake is necessary, for example in the context of rheumatoid arthritis, the intake should be discussed in detail with the doctor.