Enlargement of the Spleen or Splenomegaly

Splenomegaly (Enlargement of the Spleen): Medical History

Medical history (history of illness) is an important component in the diagnosis of splenomegaly (splenomegaly). Family history Is there a history of frequent blood/immune system disorders in your family? Social history Current medical history/systemic history (somatic and psychological complaints). What symptoms(nonspecific, mainly left upper abdominal pain/pressure sensation; rapid feeling of fullness/fullness at meals) have you … Splenomegaly (Enlargement of the Spleen): Medical History

Splenomegaly (Enlargement of the Spleen): Or something else? Differential Diagnosis

Respiratory System (J00-J99). Berylliosis – disease caused by exposure to beryllium compounds; may manifest in diverse organs. Blood, hematopoietic organs – immune system (D50-D90). Iron deficiency anemia – form of anemia caused by iron deficiency. Hemoglobinopathies – group of genetic diseases caused by disorders in the synthesis of hemoglobin (blood pigment). Hemolytic anemia – form … Splenomegaly (Enlargement of the Spleen): Or something else? Differential Diagnosis

Splenomegaly (Enlargement of the Spleen): Complications

The following are the most important diseases or complications that may be contributed to by splenomegaly (splenomegaly): Blood, blood-forming organs – Immune system (D50-D90). Hypersplenism – complication of splenomegaly; leads to increase in functional capacity beyond what is necessary; as a result, there is excessive elimination of erythrocytes (red blood cells), leukocytes (white blood cells), … Splenomegaly (Enlargement of the Spleen): Complications

Splenomegaly (Enlargement of the Spleen): Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; furthermore: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye). Abdomen (abdomen) Shape of the abdomen? Skin color? Skin texture? Efflorescences (skin changes)? Pulsations? Bowel movements? Visible vessels? Scars? … Splenomegaly (Enlargement of the Spleen): Examination

Splenomegaly (Enlargement of the Spleen): Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests. Small blood count Differential blood count Laboratory parameters 2nd order – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification. Iron metabolism parameters such as ferritin, reticulocyte hemoglobin, transferrin receptor. Inflammatory parameters – CRP (C-reactive protein). … Splenomegaly (Enlargement of the Spleen): Test and Diagnosis

Splenomegaly (Enlargement of the Spleen): Diagnostic Tests

Obligatory medical device diagnostics. Abdominal ultrasonography (ultrasound examination of abdominal organs) – for basic diagnosis. Electrocardiogram (ECG; recording of the electrical activity of the heart muscle) – for suspected cardiac involvement. Optional medical device diagnostics – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification. Computed … Splenomegaly (Enlargement of the Spleen): Diagnostic Tests

Splenomegaly (Enlargement of the Spleen): Therapy

Therapy of splenomegaly (splenomegaly) depends on the underlying disease. If the underlying disease cannot be treated or if hypersplenism occurs as a complication of splenomegaly (e.g., anemia (anemia), thrombocytopenia (lack of platelets), granulocytopenia, i.e., decrease in neutrophil granulocytes) that cannot be controlled, splenectomy (surgical removal of the spleen) is an option.