Respiratory System (J00-J99).
- Berylliosis – disease caused by exposure to beryllium compounds; may manifest in diverse organs.
Blood, hematopoietic organs – immune system (D50-D90).
- Iron deficiency anemia – form of anemia caused by iron deficiency.
- Hemoglobinopathies – group of genetic diseases caused by disorders in the synthesis of hemoglobin (blood pigment).
- Hemolytic anemia – form of anemia in which there is dissolution of blood cells.
- Idiopathic splenomegaly – splenomegaly with no apparent cause.
- Immune neutropenia – reduction of granulocytes (immune defense cells) in the blood.
- Immune thrombocytopenia – autoimmune disease associated with a decrease in the number of platelets in the blood.
- Splenic abscess – encapsulated collection of pus in the spleen.
- Splenic cyst – encapsulated cavity in the spleen.
- Pernicious anemia (synonym: Biermer’s disease) – form of anemia (anemia) based on a deficiency of vitamin B12.
- Sarcoidosis (synonyms: Boeck’s disease; Schaumann-Besnier’s disease) – systemic disease of connective tissue with granuloma formation (skin, lungs and lymph nodes).
- Sickle cell anemia (med.: Drepanocytosis; also sickle cell anemia, sickle cell anemia) – genetic disease with autosomal recessive inheritance, which affects the erythrocytes (red blood cells); it belongs to the group of hemoglobinopathies (disorders of hemoglobin; formation of an irregular hemoglobin, the so-called sickle cell hemoglobin, HbS).
- Spherocytosis (spherocytosis).
- Thalassemia – autosomal recessive hereditary synthesis disorder of the alpha or beta chains of the protein portion (globin) in hemoglobin (hemoglobinopathy/diseases resulting from impaired formation of hemoglobin).
- Α-Thalassemia (HbH disease, hydrops fetalis/generalized fluid accumulation); incidence: mostly in Southeast Asians.
- Β-Thalassemia: most common monogenetic disorder worldwide; incidence: People from Mediterranean countries, Middle East, Afghanistan, India and Southeast Asia.
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Amyloidosis – extracellular (“outside the cell”) deposits of amyloids (degradation-resistant proteins) that can lead to cardiomyopathy (heart muscle disease), neuropathy (peripheral nervous system disease), and hepatomegaly (liver enlargement), among other conditions.
- Hurler syndrome (Hurler disease) – genetic disease with autosomal recessive inheritance; most severe course of lysosomal storage disease mucopolysaccharidosis type I (MPS I), which manifests in infancy; characterized by recurrent (recurring) otitis (ear infection), gibbus (pointed hump of the spine), hip dysplasia, umbilical and inguinal hernias (hernia of the groin); obstructive and restrictive respiratory symptoms, joint contractures, and joint stiffness
- Hyperthyroidism (hyperthyroidism).
- Gaucher’s disease – hereditary disease that leads to the storage of sphingomyelin in various body tissues (sphingolipidosis).
- Niemann-Pick disease (synonyms: Niemann-Pick disease, Niemann-Pick syndrome or sphingomyelin lipidosis) – genetic disease with autosomal recessive inheritance; belongs to the group of sphingolipidoses, which in turn are classified as lysosomal storage diseases; main symptoms of Niemann-Pick disease type A are hepatosplenomegaly (liver and spleen enlargement) and psychomotor decline; in type B, no cerebral symptoms are observed.
- Storage diseases (thesaurismoses) – such as amyloidosis, glycogenosis, hemochromatosis (iron storage disease), lipoidosis, Gaucher disease, Krabbe disease, mucopolysaccharidosis, etc.
- Tangier disease – very rare genetic defect proteinemia, which leads to disorders of lipid metabolism.
Cardiovascular system (I00-I99).
- Splenic artery aneurysm – bulge in the vessel wall.
- Heart failure (cardiac insufficiency; in this case, right heart failure/right heart failure).
- Splenic vein occlusion
- Obstruction (occlusion) of vessels such as the portal vein (→ portal hypertension/portal vein hypertension) or the hepatic vein
- Subacute bacterial endocarditis (endocarditis of the heart).
Infectious and parasitic diseases (A00-B99).
- Bacterial infections, unspecified
- Schistosomiasis – worm disease (tropical infectious disease) caused by trematodes (sucking worms) of the genus Schistosoma (couple flukes).
- Echinococcosis – infectious disease caused by Echinococcus granulosus (dog tapeworm) or multilocularis (fox tapeworm).
- Ehrlichiosis – infectious disease caused by the bacterial genus Ehrlichia.
- Histoplasmosis – fungal disease caused by Histoplasma capsulatum.
- HIV infection
- Infection with the cytomegalovirus (cytomegaly)
- Infectious mononucleosis (synonyms: Pfeiffer’s glandular fever, infectious mononucleosis, mononucleosis infectiosa, monocyte angina, Pfeiffer’s disease or kissing disease (English : kissing disease) – acute disease of the lymphatic system caused by the Epstein-Barr virus (EBV).
- Leishmaniasis – tropical infectious disease caused by Leishmania.
- Malaria – infectious disease transmitted by the Anopheles mosquito.
- Rubella infection
- Sepsis (blood poisoning)
- Syphilis (Lues) – sexually transmitted infectious disease.
- Toxoplasmosis – infectious disease transmitted by the protozoan genus Toxoplasma.
- Trypanosome infection – infectious disease caused by protozoa.
- Tuberculosis (consumption)
- Viral hepatitis (inflammation of the liver)
Liver, gallbladder, and bile ducts-pancreas (pancreas) (K70-K77; K80-K87).
- Banti syndrome – disease associated with hepatomegaly and splenomegaly (enlargement of the liver and spleen); jaundice (jaundice) and ascites (abdominal dropsy).
- Liver cirrhosis (liver shrinkage) – connective tissue remodeling of the liver, leading to functional impairment.
- Pancreatic cyst – formation of a tissue cavity in the pancreas.
- Portal hypertension – increase in blood pressure in the portal vein.
- Change in the left lobe of the liver, unspecified
Musculoskeletal system and connective tissue (M00-M99).
- Juvenile rheumatoid arthritis – form of rheumatoid arthritis that occurs in children/adolescents.
- Collagenoses (group of connective tissue diseases caused by autoimmune processes) – systemic lupus erythematosus (SLE), polymyositis (PM) or dermatomyositis (DM), Sjögren’s syndrome (Sj), scleroderma (SSc), and Sharp syndrome (“mixed connective tissue disease”, MCTD).
- Felty syndrome – Severe course of rheumatoid arthritis, almost always rheumatoid factor-positive, occurring mainly in men between the ages of 20 and 40. Is accompanied by hepatosplenomegaly (liver and spleen enlargement), leukocytopenia (decrease in the number of white blood cells / leukocytes) and thrombocytopenia (decrease in the number of platelets / platelets).
- Rheumatoid arthritis (synonym: chronic polyarthritis) – most common inflammatory disease of the joints.
- Systemic lupus erythematosus (SLE) – collagenosis affecting mainly the skin and many internal organs.
Neoplasms – tumor diseases (C00-D48).
- Acute leukemia (blood cancer)
- Angioimmunoblastic lymphadenopathy – malignant (malignant) disease that is one of the non-Hodgkin’s lymphomas.
- Angiosarcoma – malignant neoplasm originating from the vessels.
- Malignant neoplasm of the spleen, unspecified.
- Chronic lymphocytic leukemia (CLL).
- Chronic myeloid leukemia (CML)
- Eosinophilic granuloma – disease belonging to the histiocytosis X group.
- Benign neoplasms such as splenic hemangiomas, splenic fibromas or splenic lymphangiomas.
- Hamartomas of the spleen – tumors caused by maldevelopment of the tissue.
- Histiocytosis-X – group of systemic diseases that are quite diverse; causally, there is a proliferation of dendritic cells.
- Colon (large intestine) tumors, unspecified.
- Lymphomas – malignant neoplasms in the lymphatic system.
- Metastases (daughter tumors) of unspecified tumors.
- Osteomyelofibrosis or other myeloproliferative neoplasms (MPN) (formerly: chronic myeloproliferative diseases (CMPE)) – progressive disease associated with obliteration of the bone marrow.
- Pancreatic (pancreas) tumor, unspecified.
- Bone marrow tumors, unspecified
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).
- Unexplained renal enlargement, unspecified
Injuries, poisoning, and other sequelae of external causes (S00-T98).
- Drug reaction, unspecified
- Bone marrow damage due to irradiation
- Serum sickness – immune complex disease that occurs after the ingestion of protein in terms of an allergic reaction.
Medication
- Interleukin-2 – immunology drug that stimulates other cytokines and B-cell proliferation at the same time.
Environmental stresses – intoxications (poisonings).
- Damage to the bone marrow by toxins, unspecified.
