Products 5α-Reductase inhibitors are commercially available in many countries in the form of film-coated tablets and capsules. Finasteride was the first agent from this group to be approved in 1993 (USA: 1992). There are two finasteride drugs on the market. One with 5 mg for the treatment of prostate enlargement (Proscar, generic) and one with … 5Α-Reductase Inhibitors
Products In many countries, no finished medicinal products containing alfatradiol are commercially available. In Germany, preparations for external use are available (e.g., Ell-Cranell). Structure and properties Alfatradiol (C18H24O2, Mr = 272.4 g/mol) or 17α-estradiol is a stereoisomer of the female sex hormone 17β-estradiol. Effects Alfatradiol inhibits the enzyme 5α-reductase, thereby inhibiting the synthesis of the … Alfatradiol
Products Alfuzosin is commercially available in sustained-release tablet form and has been approved in many countries since 1994. In addition to the original Xatral, generic versions are also available. Structure and properties Alfuzosin (C19H27N5O4, Mr = 389.45 g/mol) is a quinazoline derivative. It is present in drugs as alfuzosin hydrochloride, a white crystalline powder that … Alfuzosin
Products Finasteride is commercially available as film-coated tablets (prostate: Proscar, generic, 5 mg; hair loss: Propecia, generic, 1 mg). It has been approved in many countries since 1993. Propecia was launched five years later, in 1998. Structure and properties Finasteride (C23H36N2O2, Mr = 372.5 g/mol) is a 4-azasteroid and structurally related to testosterone. It exists … Finasteride
Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones
Symptoms Benign hyperplasia of the prostate is a typical and chronic age-related condition in men. Approximately 50% of men over 50 and 80% of men over 80 are affected. The incidence and symptoms increase with age. Age is therefore the most important risk factor. The clinical symptoms are also called “benign prostatic syndrome”, because the … Prostate Enlargement Causes and Treatment
Products Tamsulosin is commercially available in the form of sustained-release tablets and sustained-release capsules and has been approved in many countries since 1996 (Pradif, Pradif T, generics). Tamsulosin is also available as a fixed combination with the 5alpha-reductase inhibitor dutasteride (Duodart), see under dutasteride tamsulosin. In 1996, sustained-release capsules were released (Pradif). Pradif T sustained-release … Tamsulosin
Products Dutasteride is commercially available in capsule form (Avodart). It is also available in combination with the alpha blocker tamsulosin (Duodart); see dutasteride tamsulosin. The active ingredient has been approved in many countries since 2003. Generics were registered in 2017. Generic versions of Duodart were approved in 2018. Structure and properties Dutasteride (C27H30F6N2O2, Mr = … Dutasteride
Products The 5alpha-reductase inhibitor dutasteride and the alpha-blocker tamsulosin are commercially available as a fixed combination in the form of capsules (Duodart, generics). The drug has been approved in many countries since 2010. Structure and properties Dutasteride (C27H30F6N2O2, Mr = 528.5 g/mol) is a 4-azasteroid and structurally closely related to finasteride. It exists as a … Dutasteride, Tamsulosin
Definition Increased body and facial hair in women corresponding to the male hair type due to androgen-induced conversion of vellus hair to terminal hair. Symptoms Excessive and altered hair growth (thick and pigmented) on the face, chest, abdomen, legs, buttocks, and back Acne Deeper voice Increased muscle mass Decrease in breast size Androgenetic alopecia Views … Hirsutism: Excessive Hair Growth
