Products Esomeprazole is commercially available as tablets, film-coated tablets, granules for oral suspension, and injectables (Nexium, generics). It has been approved in many countries since 2000. Generics entered the market in 2012. Fixed combinations: Naproxen and esomeprazole (Vimovo, 2011). Acetylsalicylic acid and esomeprazole (Axanum, 2012), not commercially available. Structure and properties Esomeprazole (C17H19N3O3S, Mr = … Esomeprazole
Drug gastric protection Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for acute and long-term treatment of painful and inflammatory conditions. Active ingredients used include, for example, diclofenac, acetylsalicylic acid, ibuprofen, naproxen, and mefenamic acid. However, their use is limited by adverse effects that affect the upper digestive tract and are due to inhibition of prostaglandin … Stomach Protection
Products Acetylsalicylic acid is commercially available in the low dosage of 100 mg in the form of enteric-coated film-coated tablets (Aspirin Cardio, generics; in Germany and Austria, Aspirin Protect). The drug has been approved in many countries since 1992. Aspirin Cardio 300 mg is also used. In the United States, drugs with 81 mg (= … Acetylsalicylic Acid 100 mg
Products The fixed combination containing 81 mg acetylsalicylic acid and 20 mg esomeprazole was approved in many countries in June 2012 in capsule form (Axanum). In the EU, the drug has been registered since 2011. The amount of acetylsalicylic acid contained is less than in Aspirin cardio and generics, which usually contain 100 mg of … Acetylsalicylic Acid and Esomeprazole
Products The fixed combination of naproxen (500 mg) with esomeprazole (20 mg) is approved in the form of coated tablets (Vimovo, AstraZeneca AG). The drug was registered in many countries in May 2011. Naproxen is contained in the core, and esomeprazole is contained in the coating of the tablet. Structure and properties Naproxen (C14H14O3, Mr … Naproxen and Esomeprazole
