Products Indometacin is commercially available as sustained-release capsules, indometacin eye drops (Indophtal), and solution for application (Elmetacin). This article refers to oral administration. The sustained-release capsules have been on the market in many countries since 1995 (Indocid, generic). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as … Indometacin
Products Indometacin has been approved in many countries since 1999 in the form of eye drops (Indophtal, Indophtal UD). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as a white to yellow crystalline powder that is practically insoluble in water. Effects Indomethacin (ATC S01BC01) has analgesic and … Indomethacin Eye Drops
Products Aceclofenac is approved in Germany, among other countries, in the form of film-coated tablets (Beofenac). It is not registered in many countries. Structure and properties Aceclofenac (C16H13Cl2NO4, Mr = 354.2 g/mol) is structurally related to diclofenac and is partially metabolized to it. It exists as a white crystalline powder that is practically insoluble in … Aceclofenac
Products Nabumetone was commercially available in many countries in the form of film-coated tablets and soluble tablets (Balmox). It was approved in 1992 and went out of commerce in 2013, presumably for commercial reasons. Structure and properties Nabumetone (C15H16O2, Mr = 228.3 g/mol) exists as a white crystalline powder that is practically insoluble in water. … Nabumetone
Products Benoxaprofen was commercially available in tablet form (Oraflex, Opren) beginning in 1980. It was withdrawn from the market again in August 1982 because of the numerous adverse effects reported. Structure and properties Benoxaprofen (C16H12ClNO3, Mr = 301.7 g/mol) is a chlorinated benzoxazole derivative and exists as a racemate. It belongs to the propionic acid … Benoxaprofen
Products Meloxicam was commercially available in tablet form (Mobicox). It was approved in many countries since 1995. It was discontinued from distribution in 2016. Structure and properties Meloxicam (C14H13N3O4S2, Mr = 351.4 g/mol) belongs to the oxicams and is a thiazole and a benzothiazine derivative. It exists as a yellow powder that is practically insoluble … Meloxicam
Products Lysine acetyl salicylate is commercially available as powder and injectable (Aspégic, Alcacyl powder, Germany: e.g., Aspirin i.v., Aspisol). It has been approved in many countries since 1973. Migpriv, which is combined with metoclopramide for migraine, was withdrawn from the market in many countries in December 2011 see under Migpriv. Kardégic was withdrawn from the … Lysine Acetyl Salicylate
Products Ketoprofen is commercially available as a gel (Fastum). It has been approved in many countries since 1992 and in the EU since 1978. The -enantiomer dexketoprofen is available as tablets and as a solution for injection (Ketesse). This article refers to external use. After the safety of topical ketoprofen was questioned in France in … Ketoprofen
Products Ketorolac commercially available in the form of film-coated tablets, as a solution for injection (Tora-Dol), and as eye drops (Acular, generic). It has been approved in many countries since 1992. Structure and properties Ketorolac (C15H13NO3, Mr = 255.7 g/mol) is present in drugs in the form of the salt ketorolactrometamol (= ketorolactromethamine), see also … Ketorolac
Products In many countries, finished medicinal products containing the active ingredient Felbinac are currently no longer on the market (previously, for example, Dolo Target). In Germany, the cooling ThermaCare pain gel is available (UK: Traxam). Structure and properties Felbinac (C14H12O2, Mr = 212.2 g/mol) is an acetic acid derivative of biphenyl. It is present in … Felbinac
Products There are no drugs containing fenbufen on the market in many countries. Brand names include Cinopal and Lederfen, for example. Structure and properties Fenbufen (C16H14O3, Mr = 254.3 g/mol) exists as a white, fine, crystalline powder that is very sparingly soluble in water. It is a biphenyl derivative and belongs to the propionic acid … Fenbufen
Products There are currently no registered medicines containing niflumic acid in many countries. It is administered in the form of capsules and gel, among others. Structure and properties Niflumic acid (C13H9F3N2O2, Mr = 282.2 g/mol) exists as a pale yellow crystalline powder that is practically insoluble in water. It is an anthranilic acid derivative such … Niflumic Acid
