Talimogenlaherparepvec

Produte Talimogenlaherparepvec is commercially available as a suspension for injection (Imlygic). It was approved in the United States in 2015 and in the EU and Switzerland in 2016. Structure and properties Talimogenlaherparepvec is attenuated herpes simplex virus 1 (HSV-1) virus that has been genetically engineered to produce human granulocyte macrophage colony stimulating factor (GM-CSF). GM-CSF … Talimogenlaherparepvec

Herpes Simplex Encephalitis: Causes, Symptoms & Treatment

Herpes simplex encephalitis (also known as HSV encephalitis for short) is an inflammation of the brain caused by herpes simplex viruses. After a phase of nonspecific flu-like symptoms, the patient presents with characteristic neurological and neuropsychological symptoms as the disease progresses. With early treatment, the prognosis is good. What is herpes simplex encephalitis? Herpes simplex … Herpes Simplex Encephalitis: Causes, Symptoms & Treatment

Brivudine: Effects, Uses & Risks

Brivudine is a nucleoside analog used as a virostatic agent for herpes simplex type 1 and herpes zoster infections. It is the drug of choice for these indications in patients older than 50 years. What is brivudine? Brivudine is a substance from the group of nucleoside analogues and is used for herpes simplex type 1 … Brivudine: Effects, Uses & Risks

Prodrugs

What are prodrugs? Not all active pharmaceutical ingredients are directly active. Some must first be converted to the active substance by an enzymatic or non-enzymatic conversion step in the body. These are the so-called . The term was introduced by Adrien Albert in 1958. It is estimated that up to 10% of all active ingredients … Prodrugs

Chickenpox: Causes, Symptoms & Treatment

Chickenpox or varicella is a common childhood disease. This viral disease is mostly transmitted by droplet infection. The most typical symptoms are the noticeable skin rash. What is chickenpox? Chickenpox is a childhood disease transmitted by droplet infection and is caused by the varicella zoster virus. Chickenpox, also called wet pox or sheep pox, is … Chickenpox: Causes, Symptoms & Treatment

Viral Conjunctivitis

Symptoms Possible symptoms of viral conjunctivitis include unilateral or bilateral redness, itching, burning, eye tearing, a foreign body sensation, lymph node swelling, and bleeding. It is often accompanied by inflammation of the cornea (keratitis). Itching, watery eyes, bilateral findings and other allergic symptoms indicate allergic conjunctivitis. However, differentiation based on clinical signs is generally difficult … Viral Conjunctivitis

Aciclovir Effects and Side Effects

Products Aciclovir is commercially available as film-coated tablets, cream, aciclovir lip cream, injectable, and suspension (Zovirax, generic). This article refers to the film-coated tablets. Aciclovir eye ointment is currently no longer marketed in many countries. Aciclovir was developed in the 1970s by the British company Burroughs Wellcome (Elion et al. 1977). It has been approved … Aciclovir Effects and Side Effects

Aciclovir Eye Ointment

Products Zovirax ophthalmic ointment (30 mg/g) is no longer marketed in many countries as of 2019. In 2020, Xorox ophthalmic ointment (also 30 mg/g) was approved. Structure and properties Aciclovir (C8H11N5O3, Mr = 225.2 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is the prodrug of the active aciclovir … Aciclovir Eye Ointment