In holocrine secretion, glandular cells themselves become a component of a secretion by perishing during secretion. Such a mechanism is present in the human organism in the secretion of sebum. Both overproduction and underproduction of sebum can be pathological. What is holocrine secretion? Holocrine secretion is found, for example, in human sebaceous glands. The secreting … Holocrine Secretion: Function, Role & Diseases
Products Dopamine agonists are commercially available in the form of tablets, sustained-release tablets, transdermal patches, and injectables, among others. Structure and properties The first active ingredients, such as bromocriptine (Figure), were derived from ergot alkaloids. These are referred to as ergoline dopamine agonists. Later, agents with a nonergoline structure, such as pramipexole, were also developed. … Dopamine Agonists
Symptoms A wrinkled tongue is a variant of the tongue surface. It often manifests as a central longitudinal furrow from which additional, smaller, often symmetrical transverse furrows extend on either side. The transverse furrows may also occur alone. The depth and number vary interindividually. Folded tongue is usually asymptomatic, but sensitivity to sharp, acidic, or … Folded Tongue
Alkaloids are organic compounds that can affect animal and human organisms. Most alkaloids are produced by plants. What are alkaloids? The term alkaloids comes from Arabic and means plant ash. Alkaloids are naturally occurring organic compounds produced in the secondary metabolism of plants, bacteria, and fungi. These secondary metabolites, unlike the primary metabolites, are not … Alkaloids: Function & Diseases
Ergot alkaloids are naturally occurring active ingredients found primarily in the ergot fungus (Claviceps purpurea). They are used as an isolated component in various medicinal products because of their psychotropic and labor- and circulation-promoting properties. What are ergot alkaloids? The parasitic crescent-shaped cereal fungus grows mainly in grain ears after infection of the grain. Because … Ergot Alkaloids: Effects, Uses & Risks
The term G proteins refers to an inhomogeneous group of proteins that can bind the nucleotides guanosine diphosphate (GDP) and guanosine triphosphate (GTP). They perform a critical function in the transduction and “translation” of extracellular signals into and within the cell. Membrane-bound, heterotrimeric G proteins are the mediators between the extracellular and intracellular space, and … G Protein: Function & Diseases
Hypertrophic osteoarthropathy represents a disease that occurs in only a small number of individuals. In hypertrophic osteoarthropathy, sections on the diaphyses in the area of the long tubular bones on the limbs swell. The areas affected by the swellings cause pain. In addition, the toes and fingers of patients suffering from hypertrophic osteoarthropathy widen. What … Hypertrophic Osteoarthropathy: Causes, Symptoms & Treatment
Products Lanreotide is commercially available as a solution for injection (Somatuline Autogel). It has been approved in many countries since 2004. Structure and properties Lanreotide is present in the drug as lanreotide acetate. It is a synthetic octapeptide analog of somatostatin with the following structure: D-βNal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2, x(CH3COOH), where x = 1 to 2 Effects Lanreotide … Lanreotide
McCune-Albright syndrome is a neurocutaneous syndrome manifested by café-au-lait spots and disturbances in bone metabolism. The cause of the hereditary disorder is a genetic mutation in the GNAS1 gene, which encodes a regulator of cAMP. Treatment focuses on the administration of bisphosphonates. What is McCune-Albright syndrome? The neurocutaneous syndromes are hereditary disorders whose leading symptoms … McCune-Albright Syndrome: Causes, Symptoms & Treatment
Forecast If the benign tumour can be operated on, its size will determine how good the chances are of achieving a complete cure. For microadenomas the effective healing rate is 90%, for macroadenomas still 60%. All articles in this series: Acromegaly Diagnosis Forecast
Synonyms in a broader sense pituitary giant growth, growth disturbance English: acromegaly, pituitary gigantism Definition Acromegaly Acromegaly is an enlargement of the acra (see below) and the internal organs due to an increased secretion of growth hormone (somatotropin, GH (Growth Hormone)). This excessive secretion is present after the completion of longitudinal growth. Acres are for … Acromegaly
Diagnosis As with any procedure for finding a diagnosis, the medical history can provide information: Do old rings still fit, has the shoe size changed? The comparison with old photographs can help. In endocrinology (the science of hormones), various levels in the blood can be measured: Do old rings still fit, has the shoe size … Diagnosis | Acromegaly
