Effects ADH analogs (ATC H01BA) are derivatives of the antidiuretic hormone ADH (= vasopressin), which has antidiuretic and vasoconstrictor properties. The vasopressin analogs are modified to be predominantly antidiuretic or predominantly vasoconstrictor. Indications Diabetes insipidus Enuresis nocturna (bedwetting) Polyuria, polydipsia after hypophysectomy. Acute esophageal variceal bleeding (Terlipressin). Agents Desmopressin Terlipressin
Products Terlipressin is commercially available as an injectable (glypressin, haemopressin). It has been approved in many countries since 1982. Structure and properties Terlipressin (triglycyl lysine vasopressin) is a synthetic analog of vasopressin, the antidiuretic hormone (ADH). It differs from ADH in four amino acids: Terlipressin: Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly ADH: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly. Effects Terlipressin (ATC H01BA04) has vasoconstrictor properties, … Terlipressin
Products Desmopressin is commercially available as a solution for injection, in the form of nasal drops, as a nasal spray, tablets, and sublingual tablets (e.g., Minirin, Nocutil, other drugs). It has been approved in many countries since 1973. Structure and properties Desmopressin (C48H68N14O14S2, Mr = 1129.3 g/mol) is present in the drugs as desmopressin acetate, … Desmopressin
