Indications For the treatment of cardiac arrhythmias. Active ingredients Class I (sodium channel blockers): class IA: Ajmaline (off-label). Quinidine (out of trade) Procainamide (out of commerce) Class IB: Lidocaine Phenytoin (not approved for this indication in many countries). Tocainide (not commercially available in many countries). Mexiletine (not on sale in many countries). Class IC: Encainid … Antiarrhythmics
Excitation of the sinus muscle in the heart is transmitted to the working muscles of the atria, but these are electrically insulated from the ventricles, so that transmission of excitation at this point can occur only through the conduction of excitation by the atrioventricular node. Transmission through the muscle cell-containing atrioventricular node is delayed, thus … Atrioventricular Node: Structure, Function & Diseases
Antiarrhythmics are drugs used to treat cardiac arrhythmias. They are used primarily for tachycardia, an accelerated heartbeat. For bradycardia, a slowed heart response, a pacemaker is recommended rather than medication with antiarrhythmics. What are antiarrhythmic drugs? Antiarrhythmics are medications used to treat cardiac arrhythmias. These substances are largely manufactured synthetically and do not occur naturally. … Antiarrhythmic Drugs: Effects, Uses & Risks
Products Ajmaline (gilurytmal) is not on the market in many countries. Structure Ajmaline (C20H26N2O2, Mr = 326.4 g/mol) Effects Ajmaline (ATC C01BA05) has antiarrhythmic properties. Indications For the treatment of cardiac arrhythmias.
Medicinal drug Rauwolfiae radix – Rauvolfia root. Ingredients Indole alkaloids (Rauwolfia alkaloids): reserpine, ajmaline, ajmalicine. Effects Antihypertensive by depleting adrenergic, serotoninergic, and dopaminergic nerve endings. Sympatholytic Reassuring Antiarrhythmic due to sodium channel blockade (ajmaline) Indications Drug: mild essential hypertension. Reserpine as pure substance: hypertension. It is rarely used today (UAW). Ajmaline as a pure substance: … Rauvolfia
Products Alkaloids and their derivatives are contained as active ingredients in numerous medicines. They have been used medicinally for thousands of years, such as opium with morphine or coca leaves with cocaine. In 1805, a pure alkaloid was extracted for the first time by the German pharmacist Friedrich Sertürner with morphine. Structure and properties Alkaloids … Alkaloids
Ajmaline is extracted from the roots of Rauwolfia serpentina, the Indian snake root. It is available by prescription and is used to treat cardiac arrhythmias. In Germany, it is available under the trade name Gilurytmal. What is ajmaline? Ajmaline is extracted from the roots of Rauwolfia serpentina, the Indian snake root. It is available by … Ajmaline: Effects, Uses & Risks
Brugada syndrome is a congenital, autosomal-dominant inherited cardiomyopathy. The condition is one of the ion channel diseases and results from a mutation. Treatment includes implantation of an automatic defibrillator. What is Brugada syndrome? The heart pumps blood to the individual tissues of the body. The blood supply corresponds to an oxygen, nutrient and messenger supply … Brugada Syndrome: Causes, Symptoms & Treatment
