Nicomorphine

Products Nicomorphine was commercially available in the form of tablets, suppositories, and as a solution for injection (Vilan). It had been approved in many countries since 1957. It was discontinued in 2015. Structure and properties Nicomorphine (C29H25N3O5, Mr = 495.5 g/mol), like heroin, is an ester as well as a nicotinic acid derivative of morphine … Nicomorphine

Amitriptyline: Unpleasant Side Effects

The active ingredient amitriptyline is primarily used to treat depression. In addition, however, it is also suitable for the treatment of chronic pain. Like many other antidepressants, amitriptyline has side effects. These include headaches, circulatory problems, or weight gain. Get comprehensive information about the effects, side effects, dosage, contraindications and interactions of amitriptyline here. How … Amitriptyline: Unpleasant Side Effects

Amitriptyline: Further Guidance

Just as with any other active ingredient, amitriptyline must not be used under certain circumstances. This is the case, for example, if there is hypersensitivity to the active substance. Other contraindications include: Benign prostate enlargement with residual urine formation. States of confusion or agitation with sensory delusions. Acute intoxication with alcohol, painkillers, sleeping pills, or … Amitriptyline: Further Guidance

Disulfiram

Products Disulfiram is commercially available in the form of water-suspendable tablets called dispersible tablets (Antabus). It has been approved in many countries since 1949. Structure and properties Disulfiram or tetraethylthiuram disulfide (C10H20N2S4, Mr = 296.54 g/mol) is a white to almost white crystalline powder that is practically insoluble in water. Prior to its medical use, … Disulfiram

Back Pain Causes and Treatment

Symptoms Possible symptoms of acute back pain include muscle aches, tension, stabbing pain, limited mobility, and stiffness. The pain may radiate down the leg (sciatic pain), and patients may be unable to stand up straight. While acute pain is comparatively treatable, chronic back pain poses a serious quality of life and mental health problem and … Back Pain Causes and Treatment

Progressive Bulbar Paralysis: Causes, Symptoms & Treatment

In progressive bulbar paralysis, the motor cranial nerve nuclei of the trigeminal, facial, glossopharyngeal, vagus, and hypoglossal nerves die. This atrophy results in paralysis of the face and esophagus. Similar symptomatology characterizes ALS, so progressive bulbar paralysis is sometimes referred to as an ALS subtype. What is progressive bulbar paralysis? Progressive bulbar palsy is a … Progressive Bulbar Paralysis: Causes, Symptoms & Treatment

Rosacea Causes and Treatment

Symptoms Rosacea is a chronic inflammatory skin disorder of the face that typically affects the cheeks, nose, chin, and central forehead symmetrically (Figure). The skin around the eyes is left out. It occurs more often in people with fair skin and in middle age, but it can occur in any skin type and at any … Rosacea Causes and Treatment

Amitriptyline: Tricyclic Antidepressant

Products Amitriptyline is commercially available as film-coated tablets and capsules (Saroten, limbitrol + chlordiazepoxide). It has been approved in many countries since 1961. The distribution of tryptizole was discontinued in 2012. Structure and properties Amitriptyline (C20H23N, Mr = 277.4 g/mol) is present in drugs as amitriptyline hydrochloride, a white powder or colorless crystals that are … Amitriptyline: Tricyclic Antidepressant

Migraine Headache

Symptoms Migraine occurs in attacks. It may announce itself up to three days before an attack with various precursors (prodromes). These include, for example: Mood changes Fatigue Hunger Frequent yawning Irritability Aura may occur before the headache phase in up to about one-third of patients: Visual disturbances such as flickering lights, dots or lines, facial … Migraine Headache

Change in Urine Color

Symptoms A change in urine color is manifested by a deviation from the normal color of urine, which usually varies from pale yellow to amber. It may occur as a solitary sign or along with other symptoms. Urine is usually clear and not cloudy. It gets its color from urine pigments called urochromes. These are, … Change in Urine Color

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment