Products Metyrapone is commercially available in the form of capsules (Metopiron). It has been approved in many countries since 1961. Structure and properties Metyrapone (C14H14N2O, Mr = 226.27 g/mol) is a pyridine derivative. It is a white to light amber crystalline powder that is sparingly soluble in water. Effects Metyrapone (ATC V04CD01) inhibits the synthesis … Metyrapon
Physiological background Itch results from activation of specialized afferent unmyelinated C fibers in the skin. These fibers are anatomically identical to those that conduct pain but differ in function and stimulus transmission to the brain. They contain a number of receptors such as histamine receptors, PAR-2, endothelin receptor, and TRPV1, and mediators such as histamine, … Itch
Symptoms Atopic dermatitis, or neurodermatitis, is a noncontagious, chronic inflammatory skin disease that causes episodes of red, rough, dry or weeping, crusted and scaly skin. Eczema can occur all over the body and is typically accompanied by severe itching. Patients have dry skin. In infants, the disease begins on the scalp and cheeks. Depending on … Atopic Dermatitis: Eczema
Products Chlordiazepoxide was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and became the first active ingredient in the benzodiazepine group to be marketed in 1960 (Librium). In many countries, it is currently only available in combination with clidinium bromide or amitriptyline (Librax, Limbitrol). In other countries, the monopreparation Librium is still available. … Chlordiazepoxide
Amitriptyline is one of the first-line antidepressants, on the market since the early 1960s. It is administered primarily for depression associated with anxiety disorders. Another area of use is pain management. What is amitriptyline? Amitriptyline is administered primarily for depression associated with anxiety disorders. The antidepressant amitriptyline was first manufactured in 1960 and introduced to … Amitriptyline: Effects, Uses & Risks
Substance Amitriptyline belongs to the group of antidepressants. More precisely, it belongs to the group of tricyclic antidepressants. Together with the substances imipramine, clomipramine, desipramine and doxepin, amitriptyline is one of the best known and most frequently prescribed drugs in this group of substances. Every second a release of so-called messenger substances occurs between the … Amitriptyline
Fields of application The main field of application of amitriptyline is depressive disorders. However, it must be said that this substance is nevertheless more likely to be used as a second choice for the treatment of depression. First choice drugs are the so-called serotonin reuptake inhibitors. For depression associated with arousal, amitriptyline is used as … Fields of application | Amitriptyline
Contraindications Amitriptyline should not be given if patients show symptoms of an acute heart attack, if coronary artery disease is present, if cardiac insufficiency (heart failure) is diagnosed, if patients simultaneously show a conduction disorder of the heart or if a thigh block occurs. In addition, amitriptyline should not be given if there are neurological … Contraindications | Amitriptyline
Micro Labs The addition Amitriptyline Micro Labs does not denote a special dosage form of the drug but is the name of the pharmaceutical company that produces numerous drugs, among others Amitriptyline. 50 film-coated tablets Amitriptyline Micro Labs 10 mg cost a good 12 Euros, on presentation of a private prescription only 5 Euros per … Micro Labs | Amitriptyline
Why does Amitriptyline cause side effects? Why Amitriptyline makes side effects has several reasons. The main reason is that amitriptyline, as a psychotropic drug, acts centrally in the brain and thus influences the most important switch point of the human body. Therefore, under an antidepressant therapy with Amitriptyline there are always different side effects, some … Side effects of Amitriptyline
Tiredness Among the most common side effects of amitriptyline are fatigue and drowsiness. Especially at the beginning of the treatment, the side effects very often outweigh the actual antidepressant effect and patients are therefore very sleepy and tired for the first 2 weeks. The reason why amitriptyline leads to side effects such as fatigue is … Tiredness | Side effects of Amitriptyline
Side effects on the heart Patients taking amitriptyline must expect increased adverse effects, especially in the first 2 weeks. Side effects of amitriptyline that affect the heart are particularly frequent. On the one hand, it can lead to an increase in heart failure, which is why patients with such a disease are advised against taking … Side effects on the heart | Side effects of Amitriptyline
