Products Nitrazepam is commercially available in tablet form (Mogadon). It has been approved in many countries since 1965. Structure and properties Nitrazepam (C15H11N3O3, Mr = 281.3 g/mol) is a nitrated 1,4-benzodiazepine. It exists as a yellow crystalline powder that is practically insoluble in water. Nitrazepam is structurally closely related to flunitrazepam (Rohypnol). Effects Nitrazepam (ATC … Nitrazepam
Anterograde amnesia is characterized by a complete cessation, or at least a very severe reduction, in the ability to store or remember new events from the time of the disease or brain injury. Anterograde amnesia is caused either by lesions to specific brain regions or by degenerative processes of neurons in specific brain regions. What … Anterograde Amnesia: Causes, Symptoms & Treatment
Products Midazolam is commercially available as film-coated tablets and as a solution for injection (Dormicum, generic). It has been approved in many countries since 1982. Midazolam nasal spray has not yet been registered in many countries and must be prepared in a pharmacy as an extemporaneous formulation or imported. In 2012, a solution for use … Midazolam
Products In many countries, midazolam nasal spray is not yet available and registered as a finished drug product and therefore must be prepared as an extemporaneous formulation in a pharmacy or, at most, imported from abroad. It was approved in the United States in 2019 (Nayzilam). See also under diazepam nasal spray. Structure and properties … Midazolam Nasal Spray
Definition – What is a Korsakov syndrome? The Korsakow syndrome is a form of the so-called anamnestic syndromes, which is characterized by severe memory disorders. The main focus of the symptoms is that new content can no longer be transferred to the memory (anterograde amnesia). It is also typical that affected persons fill the memory … Korsakov Syndrome
Diagnosis The greatest importance in the diagnosis of Korsakov’s syndrome is attached to the clinical picture of the disease. Thus, an experienced physician can suspect the presence of Korsakov’s syndrome after a detailed medical history, guided by the typical memory disorder. This is particularly likely to occur if the patient or relatives report excessive alcohol … Diagnosis | Korsakov Syndrome
How do you distinguish Korsakow syndrome from dementia? The Korsakow syndrome is generally assigned to the so-called anamnestic syndromes and not to the form of dementia. While the marked decrease in memory and disorientation can also be signs of dementia, the two groups of diseases differ significantly in other aspects. Anamnestic syndromes, such as the … How do you distinguish Korsakow syndrome from dementia? | Korsakov Syndrome
This is the final stage of a Korsakow syndrome The final stage of Korsakov’s syndrome can be very similar to forms of dementia. Patients are often no longer able to manage their everyday life on their own and are dependent on outside help in almost all areas of everyday life. In addition, the depression-like symptoms … This is the final stage of a Korsakow syndrome | Korsakov Syndrome
Prognosis vs. life expectancy The life expectancy of those affected is not limited by the Korsakow syndrome itself. However, if the development of the disease is due to excessive alcohol consumption, a limited prognosis must often be given. This is mainly due to the long-term damage caused by alcohol consumption, such as liver damage. However, … Prognosis vs. life expectancy | Korsakov Syndrome
Products Chlordiazepoxide was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and became the first active ingredient in the benzodiazepine group to be marketed in 1960 (Librium). In many countries, it is currently only available in combination with clidinium bromide or amitriptyline (Librax, Limbitrol). In other countries, the monopreparation Librium is still available. … Chlordiazepoxide
