Interactions with Grapefruit Juice

Background That grapefruit juice can cause drug-drug interactions was discovered by chance in a clinical trial in 1989 and confirmed in an experiment by the same research group in 1991 (Bailey et al, 1989, 1991). This showed that simultaneous ingestion of grapefruit juice with the calcium channel blocker felodipine significantly increases the bioavailability of felodipine. … Interactions with Grapefruit Juice

Bupropion: Effects, Uses & Risks

The drug bupropion is assigned to the class of antidepressants. It is also used to treat nicotine dependence. What is bupropion? The drug bupropion is assigned to the antidepressant drug class. Bupropion is a selective dopamine and norepinephrine reuptake inhibitor (NDRI). It also marginally serves to inhibit the reuptake of serotonin. Prior to 2000, bupropion … Bupropion: Effects, Uses & Risks

Phenytoin: Effects, Uses & Risks

Phenytoin is a drug in the anticonvulsant drug class. Depending on its use, phenytoin is also classified as an antiarrhythmic agent. What is phenytoin? Anticonvulsants are used to inhibit impulses in the CNS to prevent incipient seizures. Phenytoin is a drug used primarily to treat epilepsy. However, the substance is also used for the treatment … Phenytoin: Effects, Uses & Risks

Photosensitivity

Symptoms Photosensitivity often manifests like sunburn in extensive skin redness, pain, a burning sensation, blistering, and hyperpigmentation after healing. Other possible skin reactions include eczema, itching, urticaria, telangiectasia, tingling, and edema. The nails may also be affected less frequently and may peel off in front (photoonycholysis). The symptoms are limited to the areas of the … Photosensitivity

Adenosine

Products Adenosine is commercially available as a solution for injection (Krenosin). It has been approved in many countries since 1992. Structure and properties Adenosine (C10H13N5O4, Mr = 267.2 g/mol) exists as a white crystalline powder that is sparingly soluble in water at room temperature and more soluble in hot water. Effects Adenosine (ATC C01EB10) is … Adenosine

Myopathy: Causes, Symptoms & Treatment

Myopathies are muscle diseases. In most cases, the striated skeletal muscles are affected. For example, muscular dystrophies or myotonic syndromes belong to the group of myopathies. What are myopathies? The term myopathy comes from Greek and means muscle disease. Accordingly, myopathies are diseases of the muscles. They usually affect the striated muscles of the skeleton. … Myopathy: Causes, Symptoms & Treatment

Fenoterol

Products Fenoterol is commercially available in combination with ipratropium bromide as a metered-dose inhaler (Berodual N). Berotec N is no longer on the market. Fenoterol has been approved in many countries since 2000. Structure and properties Fenoterol is present in drugs as fenoterol hydrobromide (C17H22BrNO4, Mr = 384.3 g/mol) is present, a white crystalline powder … Fenoterol

Aloe

Stem plant Asphodelaceae. Medicinal drug Curaçao aloe is the juice of (PhEur) Cape aloe thickened to dryness. Ingredients Anthranoids: aloin A and aloin B, aloinoside A and B. Preparations Aloe barbadensis et capensis Aloe barbadensis folii recentis extractum oleosum Aloes extractum aquosum siccum Aloes extractum siccum normatum PhEur Swedish bitters Numerous cosmetics Effects Laxative Indications … Aloe

Diltiazem: Effects, Uses & Risks

Diltiazem is the name given to a certain calcium antagonist. The drug is used to treat cardiovascular disease. What is diltiazem? Diltiazem is the name given to a certain calcium antagonist. The drug is used to treat cardiovascular disease. Diltiazem is an antiarrhythmic drug that belongs to the calcium antagonists or calcium channel blockers. The … Diltiazem: Effects, Uses & Risks

Labetalol: Effects, Uses & Risks

Labetalol is a drug used to treat high blood pressure. It is effective as both an alpha and beta blocker. Labetalol is used effectively in the treatment of hypertensive emergencies, postoperative hypertension, phächromozotome-associated hypertension, and rebound hypertension. Common adverse effects include headache, dyspepsia, dizziness, nausea, lethargy, nasal congestion, and erectile dysfunction. What is labetalol? Labetalol … Labetalol: Effects, Uses & Risks

Ropivacaine

Products Ropivacaine is commercially available as a solution for injection (Naropin, generic). It has been approved in many countries since 1997. Structure and properties Ropivacaine (C17H26N2O, Mr = 274.4 g/mol) is present in drugs as ropivacaine hydrochloride monohydrate. It was developed as a pure -enantiomer and belongs to the lipophilic amide-type local anesthetics. Ropivacaine is … Ropivacaine

Amiodarone (Nexterone) for Arrhythmia

Products Amiodarone is commercially available in tablet form and as a solution for injection (Cordarone, generics). It has been approved in many countries since 1968. Structure and properties Amiodarone (C25H29I2NO3, Mr = 645.3 g/mol) is an iodinated benzofuran derivative derived from khellin. It is present in drugs as amiodarone hydrochloride, a white, fine, crystalline powder … Amiodarone (Nexterone) for Arrhythmia