Zonisamide

Products Zonisamide is commercially available in the form of capsules (Zonegran). It has been approved in many countries since 2006. Structure and properties Zonisamide (C8H8N2O3S, Mr = 212.2 g/mol) is a benzisoxazole derivative and a sulfonamide. It exists as a white powder that is soluble in water. Effects Zonisamide (ATC N03AX15) has anticonvulsant and antiepileptic … Zonisamide

Oxcarbazepine

Products Oxcarbazepine is available in the form of film-coated tablets, sustained-release tablets, and as a suspension and commercially (Trileptal, Apydan extent). It has been approved in many countries since 1997. Structure and properties Oxcarbazepine (C15H12N2O2, Mr = 252.3 g/mol) exists as a white to faint orange crystalline powder and is practically insoluble in water. Oxcarbazepine … Oxcarbazepine

Benzodiazepines Effects and Side Effects

Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects

Retigabine (Ezogabine)

Products Retigabine was approved in many countries as film-coated tablets since 2011 (Trobalt). In the United States, it is referred to as ezogabine. It was discontinued in 2017. Structure Retigabine (C16H18FN3O2, Mr = 303.3 g/mol) is a carbamate that was developed starting from the analgesic flupirtine. The free primary amino group is -glucuronidated (see below). … Retigabine (Ezogabine)

Sultiam

Products Sultiam is commercially available in the form of film-coated tablets (Ospolot). It has been approved in many countries since 2003. In Germany, it was approved as early as 1998. In English, it is also referred to as resp. Structure and properties Sultiam (C10H14N2O4S2, Mr = 290.4 g/mol) is a sulfonamide derivative that is structurally … Sultiam

Potassium Bromide

Products Potassium bromide is commercially available in Germany in the form of 850 mg tablets (Dibro-Be Mono). In many countries, apart from alternative medicine preparations, no medicines containing potassium bromide are currently available. The drugs can be imported or possibly prepared as an extemporaneous formulation. Kalium bromatum is the Schüssler salt no. 14. Structure and … Potassium Bromide

Promethazine

Products In many countries, drugs containing promethazine are currently no longer on the market. The last product to be withdrawn from the market was Rhinathiol promethazine with the expectorant carbocisteine on January 31, 2009. However, medicines are still available in many countries. The original drug is Phenergan. Promethazine was developed in the 1940s at Rhône-Poulenc, … Promethazine

Valproic Acid: Drug Effects, Side Effects, Dosage and Uses

Products Valproic acid is commercially available as tablets, mini-tablets (minipacks), capsules, injectable, syrup, and solution (Depakine, generic). It has been approved in many countries since 1972. Structure and properties Valproic acid (C8H16O2, Mr = 144.2 g/mol) or 2-propylpentanoic acid is a colorless to slightly yellowish, clear, and slightly viscous liquid that is very slightly soluble … Valproic Acid: Drug Effects, Side Effects, Dosage and Uses

Pregabalin

Products Pregabalin is commercially available in capsule form and as an oral solution (Lyrica, generics). It was approved in the United States and EU in 2004 and in many countries in 2005. Structure and properties Pregabalin (C8H17NO2, Mr = 159.2 g/mol) exists as a white crystalline powder that is soluble in water. It was developed … Pregabalin

Carbamazepine Effects and Side Effects

Products Carbamazepine is commercially available as tablets, sustained-release tablets, suspension, and syrup (Tegretol, generics). It has been approved in many countries since 1963. Structure and properties Carbamazepine (C15H12N2O, Mr = 236.3 g/mol) exists as a white crystalline powder that is very sparingly soluble in water. It has a tricyclic structure and an active metabolite, carbmazepine-10,11-epoxide. … Carbamazepine Effects and Side Effects

Omeprazole: Drug Effects, Side Effects, Dosage and Uses

Products Omeprazole is commercially available in tablet, capsule, and injection/infusion forms and has been approved in many countries since 1988. In addition to the original Antramups, generics and the -enantiomer esomeprazole (Nexium) are also commercially available. At the end of March 2010, after pantoprazole, omeprazole was also approved for self-medication in many countries. In the … Omeprazole: Drug Effects, Side Effects, Dosage and Uses

Felbamate

Products Felbamate is commercially available in tablet and suspension form (Taloxa). It has been approved in many countries since 1997. Structure and properties Felbamate (C11H14N2O4, Mr = 238.2 g/mol) is a dicarbamate. It exists as a white crystalline powder with a typical odor that is sparingly soluble in water. Effects Felbamate (ATC N03AX10) has antiepileptic … Felbamate