Products Eslicarbazepine has been approved in tablet form in the EU since 2009, in the United States since 2013, and in many countries in 2020 (Zebinix, Aptiom). Structure and properties Eslicarbazepine (C15H14N2O2, Mr = 254.3 g/mol) is present in drugs in the form of the prodrug eslicarbazepine acetate, which is hydrolyzed in the body after … Eslicarbazepine
Products Tiagabine was commercially available in the form of film-coated tablets (gabitril). It was approved in many countries in 1996 and went off the market in June 2012. Structure and properties Tiagabine (C20H25NO2S2, Mr = 375.5 g/mol) is a piperidine and thiophene derivative. It exists as a white crystalline powder that is sparingly soluble in … Tiagabine
Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant
As the name itself expresses, bleeding gums (also gum bleeding) is mostly recognized by the traces of blood in the mouth. These are mostly noticed when brushing the teeth with rinsing out the toothpaste. What is bleeding gums? Bleeding gums are noticeable by blood and pain when brushing teeth, traces of blood when biting into … Bleeding Gums: Causes, Treatment & Help
Definition Tegretal® is a drug containing the active ingredient carbamazepine. It is the world’s best-selling drug for the treatment and prevention of seizures. Tegretal® is available only on prescription. There are two major areas of application for Tegretal®. One is seizure-like disorders such as epileptic seizures, non-epileptic seizures in patients with multiple sclerosis and seizures … Tegretal®
Contraindications Tegretal® must not be taken if A delayed transmission of excitation to the heart takes place (AV block), There is damage to the bone marrow, A metabolic disease such as acute porphyria is known or So-called monoaminooxidase inhibitors can be taken to treat depression. Interactions Tegretal® is broken down by enzymes in the liver, … Contraindications | Tegretal®
Products Lorazepam is commercially available as tablets, meltable tablets, and a solution for injection. In addition to the original Temesta, generics and a combination product with the sedative antihistamine diphenhydramine are also available (Somnium). Lorazepam has been approved in many countries since 1973. Structure and properties Lorazepam (C15H10Cl2N2O2, Mr = 321.2 g/mol) is a white … Lorazepam
Products Perampanel is commercially available in the form of film-coated tablets (Fycompa). It has been approved in many countries since late 2012. In 2020, an oral suspension was also registered. Structure and properties Perampanel (C23H15N3O, Mr = 349.4 g/mol) is a pyridine derivative. It exists in the drug as a white to yellowish powder that … Perampanel
Products Rufinamide is commercially available as film-coated tablets and as an oral suspension (Inovelon). It was approved in the EU in 2007 and in many countries in 2009. The suspension was registered in many countries in 2012. Structure and properties Rufinamide (C10H8F2N4O, Mr = 238.2 g/mol) is a methyl triazole carboxamide. It exists as a … Rufinamide
Products Phenobarbital is commercially available in tablet form and as a solution for injection (aphenylbarbit, phenobarbital Bichsel). It was approved in many countries in 1944. Luminal has been off the market in many countries since late August 2011. Barbexaclone (maliasin), a fixed combination of phenobarbital and L-propylhexedrine, is also no longer available. Structure and properties … Phenobarbital
Products Primidone is commercially available in tablet form (Mysoline). It has been approved in many countries since 1952. Structure and properties Primidone (C12H14N2O2, Mr = 218.3 g/mol) is a white crystalline powder that is very sparingly soluble in water. Effects Primidone (ATC N03AA03) has antiepileptic properties. Indications Grand mal, psychomotor epilepsy, focal seizures, petit mal, … Primidone
Products Vigabatrin is commercially available as film-coated tablets and as a powder (Sabril). It has been approved in many countries since 1992. Structure and properties Vigabatrin (C6H11NO2, Mr = 129.2 g/mol) is structurally a GABA analog. It exists as a white powder that is readily soluble in water. Effects Vigabatrin (ATC N03AG04) has antiepileptic properties. … Vigabatrin