How rifampicin works The antibiotic rifampicin is effective against various strains of bacteria. It blocks a bacterial enzyme (RNA polymerase) that the germs need to produce vital proteins. As a result, they die. The antibiotic therefore has a bactericidal (bactericidal) effect. Because it is well distributed in the body – rifampicin also has a good … Rifampicin: Effect, Applications, Side Effects
How sulfasalazine works Sulfasalazine is used as a basic treatment for rheumatic diseases and inflammatory bowel disease (IBD). Rheumatism is a group of autoimmune diseases. This means that the immune system attacks and breaks down the body’s own tissue (such as joint cartilage). Chronic inflammatory bowel diseases are also caused by a faulty reaction of … Sulfasalazine: Effects, Applications, Side Effects
How levonorgestrel works As a progestogen, levonorgestrel influences the body’s regulation of the menstrual cycle. This can be roughly divided into two phases, each of which lasts about two weeks: the follicular phase and the luteal phase. Ovulation heralds the second half of the cycle, the luteal phase. The ovary or the ovarian follicle that … Levonorgestrel: Effects, applications, side effects
How bezafibrate works Bezafibrate and other fibrates activate certain docking sites for endogenous messenger substances in liver cells, the so-called peroxisome proliferator-activated receptors (PPAR). These receptors regulate the activity of genes involved in fat and carbohydrate metabolism. Overall, the intake of bezafibrate primarily lowers triglycerides. At the same time, the LDL value is slightly lowered … Bezafibrate: Effects, Applications, Side Effects
What effect has mountain pine? The young twigs and needles of mountain pine (leg pine) contain an essential oil with components such as pinene, carene and limonene. It smells very aromatic and has secretion-dissolving, blood circulation-promoting (hyperemic) and weak germ-reducing (antiseptic) effects. Therefore, mountain pine (more precisely, mountain pine oil) has long been used to … Mountain Pine: Effects and Applications
How Bisacodyl works Bisacodyl is a “prodrug”, i.e. a precursor of the actual active substance. It is converted by the bacteria in the large intestine into the active form BHPM. This inhibits the absorption of sodium and water from the stool into the blood and promotes the release of water and electrolytes into the intestine. … Bisacodyl: Effects, Applications, Side Effects
How phenylbutazone works Phenylbutazone inhibits the formation of prostaglandins. These tissue hormones are significantly involved in the development of pain, fever and inflammatory reactions. The active ingredient blocks enzymes that are essential for the synthesis of prostaglandins (cyclooxygenases, or COX for short). In this way, phenylbutazone has analgesic (analgesic), antipyretic (antipyretic) and anti-inflammatory (antiphlogistic) effects. … Phenylbutazone: Effects, Applications, Side Effects
How imatinib works As a so-called BCR-ABL kinase inhibitor, imatinib inhibits an enzyme that is overactive in cancer cells. The activity of this tyeosin kinase is thereby downregulated so that it again corresponds to that in healthy cells. Because healthy cells do not have this pathologically altered enzyme, imatinib only works on cancer cells. The … Imatinib: Effects, Applications, Side Effects
How cotrimoxazole works Cotrimoxazole is a combination preparation of the antibiotics sulfamethoxazole and trimethoprim. Both substances inhibit the formation of folic acid in certain bacteria and fungi. This is needed for the synthesis of some building blocks of genetic material (thymidine and purines). Cotrimoxazole interrupts folic acid synthesis in two different ways: Trimethoprim inhibits the … Cotrimoxazole: Effects, Applications, Side Effects
How spironolactone works Spironolactone is an active substance from the class of aldosterone inhibitors (antagonist). It blocks the action of the hormone aldosterone and thus has antihypertensive, antiandrogenic and mild diuretic (diuretic) properties. The blood is filtered through the renal corpuscle, retaining larger components such as proteins or whole blood cells and filtering out smaller … Spironolactone: Effects, Applications, Side Effects
How cefixime works Cefixime has a bactericidal effect, i.e. it can kill bacteria. Bacteria protect themselves from harsh environmental influences by forming a solid cell wall in addition to a cell membrane (as animal and human cells also have). This mainly gives the germs increased resistance to external influences such as varying salt concentrations in … Cefixime: Effects, Applications, Side Effects
How colchicine works Colchicine can effectively relieve the sometimes very severe pain of acute gout attacks. Gout is a metabolic disease in which the concentration of uric acid in the blood is elevated. If it exceeds a certain limit, some of the uric acid precipitates in the form of crystals and is deposited in the … Colchicine: Effect, Applications, Side Effects
