Thiazide Diuretics

Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics

Triamteren

Products Drugs containing triamterene are no longer on the market in many countries. Triamterene was included in Diucomb, Diuricomplex, Dyazide, Dyrenium, and Dyrenium compositum, capsules (+ benzthiazide). Structure and properties Triamterene (C12H11N7, Mr = 253.3 g/mol) Effects Triamterene (ATC C03DB02) is diuretic by inhibiting sodium reabsorption in the distal tubule. Indications Oedema, arterial hypertension.

Benzothiazide

Products Benzthiazide is no longer commercially available in many countries. It was formerly included in combination with triamterene in Dyrenium compositum. Structure and properties Benzthiazide (C15H14ClN3O4S3, Mr = 431.9 g/mol) Effects Benzthiazide has diuretic properties. Indications Edema Arterial hypertension