Products Canrenone is commercially available as an injectable (Soldactone). It has been approved in many countries since 1975. Structure and properties Canrenone (C22H28O3, Mr = 340.5 g/mol) is an active metabolite of spironolactone (aldactone) and, unlike the latter, is soluble in water. Canrenone is present in drugs as potassium canrenoate, the potassium salt of canrenoic … Canrenon
Products Amiloride is sold exclusively in fixed combination with the diuretic hydrochlorothiazide in tablet form. The original Moduretic is no longer available in many countries, but generics are available. Structure and properties Amiloride is present in drugs as amiloride hydrochloride (C6H9Cl2N7O – 2 H2O, Mr = 302.1 g/mol) is present, a pale yellow to greenish … Amiloride
Products Drugs containing triamterene are no longer on the market in many countries. Triamterene was included in Diucomb, Diuricomplex, Dyazide, Dyrenium, and Dyrenium compositum, capsules (+ benzthiazide). Structure and properties Triamterene (C12H11N7, Mr = 253.3 g/mol) Effects Triamterene (ATC C03DB02) is diuretic by inhibiting sodium reabsorption in the distal tubule. Indications Oedema, arterial hypertension.
