Beta Lactam Antibiotics against Bacterial Infections
Effect Beta-lactam antibiotics have bacteriostatic to bactericidal properties. They inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). PBPs include transpeptidases, which are responsible for cross-linking peptidoglycan chains during cell wall synthesis. Some beta-lactams can be degraded and thus inactivated by the bacterial enzyme beta-lactamase Indications The spectrum of beta-lactam antibiotics ranges from … Beta Lactam Antibiotics against Bacterial Infections