Products Laxatives are available in numerous dosage forms. These include, for example, tablets, drops, suppositories, powders, granules, solutions, syrups and enemas. Structure and properties Laxatives do not have a uniform chemical structure. However, groups can be identified (see below). Effects Laxatives have laxative properties. They stimulate bowel emptying by different mechanisms depending on the active … Laxative
Products Bisacodyl is commercially available in the form of enteric-coated tablets (dragées) and suppositories (Dulcolax, generics). It has been approved in many countries since 1957. Structure and properties Bisacodyl (C22H19NO4, Mr = 361.39 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a diphenylmethane and triarylmethane derivative. Bisacodyl is … Bisacodyl
Products Sodium picosulfate is commercially available in the form of tablets, soft capsules (pearls), and drops (e.g., Laxoberon, Dulcolax Picosulfate). It has been approved in many countries since 1973. Structure and properties Sodium picosulfate (C18H13NNa2O8S2, Mr= 481.41 g/mol) is structurally closely related to bisacodyl. The difference is that it is esterified with sulfuric acid instead … Sodium Picosulfate
Symptoms Irritable bowel syndrome is a functional bowel disorder that manifests itself in the following persistent or recurrent symptoms: Lower abdominal pain or cramping Diarrhea and/or constipation Flatulence Change in bowel habits, impaired defecation. Incontinence, urge to defecate, feeling of incomplete emptying. The symptoms improve with defecation. Some patients suffer mainly from diarrhea, others from … Irritable Bowel Syndrome Causes and Treatment
Products Several drugs are commercially available as enteric-coated tablets. Listed below are active ingredients that are administered with this dosage form: Proton pump inhibitors such as pantoprazole and esomeprazole. Some painkillers, e.g., NSAIDs such as diclofenac Digestive enzymes: pancreatin Laxative: bisacodyl Salicylates: mesalazine, acetylsalicylic acid 100 mg. Structure and properties Enteric coated tablets belong to … Enteric-Coated Tablets
Definition Medication overuse involves using self-purchased or physician-prescribed medications for too long, too much, or too frequently. The duration of therapy prescribed by a healthcare professional or by the professional and patient information is exceeded, the maximum single or daily dose is too high because of a dose increase, or the dosing interval is too … Medication Overuse
Products Phenolphthalein has been included in many laxatives in the past, for example in Reguletts tablets (100 mg) in many countries. Sales of the last drug containing phenolphthalein (Paragar Emulsion) will be discontinued in many countries in 2018. Structure and properties Phenolphthalein (C20H14O4, Mr = 318.3 g/mol) exists as a white powder that is practically … Phenolphthalein