Substance Nifedipine is a calcium antagonist of the dihydropyridine group and is used to treat high blood pressure (hypertension) and heart sensation (angina pectoris). Fields of application In Germany, nifedipine is used to treat essential hypertension (high blood pressure), hypertensive crises (hypertensive crises), heart sensation (angina pectoris) and Raynaud’s syndrome. Side effects When taking nifedipine, … Nifedipine
Symptoms Urinary incontinence manifests as involuntary leakage of urine. The common problem poses a psychosocial challenge for those affected, which can lead to changes in personal activities and a loss of quality of life. Risk factors include female gender, age, obesity, and numerous medical conditions. Causes Urinary incontinence can occur as a result of pathologic, … Urinary Incontinence: Causes and Treatment
Symptoms and causes 1. sunstroke results from excessive sun exposure to the head, causing heat buildup and irritation of the meninges (aseptic meningitis): Headache Neck stiffness Nausea, vomiting Feeling of heat in the head Dizziness, restlessness 2. In heat exhaustion, there is an overheating of the body with a body temperature between 37 to 40°C. … Sunstroke, Heat Exhaustion and Heat Stroke
General information Amlodipine is an antihypertensive drug. In addition to its use as a basic medication for high blood pressure (arterial hypertension), it is also used to treat chronic tightness in the chest (angina pectoris) and to prevent acute attacks of angina pectoris in Prinzmetal angina. Pharmacologically, it belongs to the class of calcium channel … Amlodipine
What should I watch out for when stopping this medicine? Amlodipine is one of the drugs that lower blood pressure. All drugs in this group must not be suddenly discontinued. Taking the drug reduces the number of so-called receptors in the body, which otherwise keep blood pressure low. The body needs some time to readjust … What should I watch out for when stopping this medicine? | Amlodipine
Contraindications Amlodipine should only be given with special caution to patients with a narrowing of the aortic valve (see aortic valve stenosis), as the drug’s blood pressure-lowering effect can lead to reduced blood flow to the heart, which in turn could trigger a heart attack. In patients with a damaged liver, a lower starting dose … Contraindications | Amlodipine
Are amlodipine tablets halvable? The divisibility of amlodipine tablets depends on the preparation. In the package insert it is noted in each case if the tablets can be divided in half. For example, the tablets of the preparation Amlodipine – 1 A Pharma® 5mg Tablets N can be divided in half. Amlodipine tablets are available … Are amlodipine tablets halvable? | Amlodipine
P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein
Substance Adalat® is a substance that falls into the group of calcium antagonists. Together with the drug Bayotensin, it is one of the most popular representatives of calcium antagonists. Active substance The active ingredient of Adalat® is nifedipine. There are a number of other active ingredients, such as amlodipine, felodipine, isradipine, nicardipine, nimodipine, nisoldipine and … Adalat
Metabolism Adalat® is metabolized up to 90% after absorption. It then reaches the liver where a large proportion is already metabolized and is no longer available for the actual effect. The proportion that can still be effective in the body is around 45-65%. Interaction with other drugs Medications that also lower blood pressure should only … Metabolism | Adalat
Dosage In case of stable angina pectoris, arterial hypertension or Raynaud’s syndrome, 3 times 5-10 mg should be given. If necessary, the medication can also be increased. The maximum dose is 60 mg a day. In a sustained release form (i.e. the active substance is released over a certain period of time) 2x 20 mg … Dosage | Adalat
