What is cholinesterase? Cholinesterase (ChE) is an enzyme that cleaves various chemical compounds in the body, namely cholinesters. There are two subtypes of cholinesterase, ChE I and ChE II. However, only the latter, also called pseudocholinesterase, can be measured in the blood. It is produced in the liver. Therefore, it is also a good marker … Cholinesterase (ChE): Importance and Normal Values
Cholinesterase inhibitors are components of various drugs that can be used for a wide range of diseases due to their many different modes of action. Cholinesterases increase the activity of certain cell compounds, which are located in the brain as well as in various organs such as the eyes or the bladder. The available cholinesterase … What are cholinesterase inhibitors?
The active ingredient and the effect of cholinesterase inhibitors Cholinesterase inhibitors are a group of active ingredients that differ slightly in their chemical structure but are characterized by the same basic action. The site of action is the connections between nerve cells (synapses) and the connection between nerve and muscle cells (motor end plate). There, … The active ingredient and the effect of cholinesterase inhibitors | What are cholinesterase inhibitors?
Contraindications – When should a cholinesterase inhibitor not be given? Cholinesterase inhibitors must not be given for different diseases on different organs, as otherwise the disease may worsen and sometimes life-threatening consequences may result. First of all, there are diseases of the heart where there is a disturbance of the electrical impulse conduction (AV-BLock) or … Contraindications – When should a cholinesterase inhibitor not be given? | What are cholinesterase inhibitors?
Poisoning with a cholinesterase inhibitor Poisoning with a cholinesterase inhibitor can occur as a result of excessive use of the drug. Depending on the amount of overdose, different signs of poisoning may appear. Moderate overdose may result in increased tear and saliva flow, muscle twitching, decreased respiratory drive and hypothermia. In case of a severe … Poisoning with a cholinesterase inhibitor | What are cholinesterase inhibitors?
Definition – What is cholinesterase deficiency? Cholinesterase is an enzyme (a substance that speeds up chemical reactions in the body, usually a protein) and is produced in the liver. It plays an important role in the transmission of impulses from nerves to, for example, muscles (see: Motor End Plate). If the liver is damaged by … Cholinesterase deficiency
Effects of cholinesterase deficiency under local anesthesia With local anaesthesia, a cholinesterase deficiency has the consequence that certain local anaesthetics are broken down more slowly. This results in a prolonged anaesthesia of the region, but the fact that the drug has a longer duration of action in the body can also lead to further side … Effects of cholinesterase deficiency under local anesthesia | Cholinesterase deficiency